GRIP

Infections in Primary Care Research Group

The primary objective of the group is to define a policy of antibiotics in primary care, in order to achieve a more reasoned prescription of antibiotics in infectious diseases in primary care, identifying the subgroups of patients who really need them . Other objectives are the microbiological aspects of the most prevalent community germs, to diagnose precisely the different infectious processes with the help of rapid diagnostic methods, to better identify whether the aetiology is bacterial or viral and to better understand the level of resistances of common microorganisms. The group is made up of family doctors who work in different lines of research for infectious diseases in primary care. It is planned in the future to also have professionals in the field of microbiology, pneumology, nursing staff and statisticians. We have collaborations with: hospitals (Vall d'Hebron Hospital in Barcelona and Joan XXIII Hospital in Tarragona), universities (University of Barcelona, Autonomous University of Barcelona, Rovira i Virgili University, University of Cardiff, University of Oxford and University of Copenhagen) and scientific societies (Camfic, semFYC and WONCA). This group includes GPs that investigate various aspects of infectious diseases in primary care, together with other professionals such as specialists in respiratory diseases, nurses and statisticians.

The group participates in the following projects

PI: Llor Vilà, Carles. Effectiveness and cost-effectiveness of Improving clinicians' diagnostic and communication Skills on Antibiotic prescribing Appropriateness in patients with acute Cough in primary care in CATalonia. Funding: Fundacio La Marato de TV3. Duration: 2019 - 2021

PI: Llor Vilà, Carles. Community acquired acute respiratory tract infection (CA-ARTI) in community care in Europe: point prevalence audit study (PPAS) of presentation and management. Funding: University of Oxford. Duration: 2019 - 2020

PI: Llor Vilà, Carles. Efectividad del tratamiento antitusígeno, anticolinérgico y miel versus práctica habitual en adultos con bronquitis aguda no complicada. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Pueyo Sanchez, Maria Jesús. Programa comunitari de prevenció de fractures osteoporòtiques (APROP). Funding: Amgen, S.A. Duration: 2018 - 2019

PI: Llor Vilà, Carles. Regulating Resistance, Resisting Regulation: New regimes to tackle drug resistant infections in European and Asian healthcare systems. Funding: ICS - Institut Català de la Salut. Duration: 2018 - 2019

PI: Llor Vilà, Carles. Estudio europeo multicéntrico de enfermedades infecciosas respiratorias: Infecciones Respiratorias Agudas en Adultos. Estudi MERMAIDS. Funding: University of Oxford. Duration: 2017 - 2019

The group participates in the following publications

Butler CC, Gillespie D, White P, Bates J, Lowe R, Thomas-Jones E, Wootton M, Hood K, Phillips R, Melbye H, Llor C, Cals JWL, Naik G, Kirby N, Gal M, Riga E, Francis NA. C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations. N. Engl. J. Med. 2019 07; 381(2):111-120. doi:10.1056/NEJMoa1803185. PMID:31291514. IF: 70,670.

Cots JM, Moragas A, García-Sangenís A, Morros R, Gomez-Lumbreras A, Ouchi D, Monfà R, Pera H, Pujol J, Bayona C, de la Poza-Abad M, Llor C. Effectiveness of antitussives, anticholinergics or honey versus usual care in adults with uncomplicated acute bronchitis: a study protocol of an open randomised clinical trial in primary care. BMJ Open. 2019 May; 9(5):e028159. doi:10.1136/bmjopen-2018-028159. Epub 2019 May 16. pmc:PMC6530348. PMID:31101700. IF: 2,376.

de la Poza Abad M, Mas Dalmau G, Gich Saladich I, Martínez García L, Llor C, Alonso-Coello P. Use of delayed antibiotic prescription in primary care: a cross-sectional study. BMC Fam Pract. 2019 Mar; 20(1):45. doi:10.1186/s12875-019-0934-7. Epub 2019 Mar 26. pmc:PMC6434640. PMID:30914044. IF: 2,431.

Llor C, Pérez A, Carandell E, García-Sangenís A, Rezola J, Llorente M, Gestoso S, Bobé F, Román-Rodríguez M, Cots JM, Hernández S, Cortés J, Miravitlles M, Morros R. Efficacy of high doses of penicillin versus amoxicillin in the treatment of uncomplicated community acquired pneumonia in adults. A non-inferiority controlled clinical trial. Aten Primaria. 2019 Jan;51(1):32-39. doi: 10.1016/j.aprim.2017.08.003. Epub 2017 Oct 20. PubMed PMID: 29061311; PubMed Central PMCID: PMC6836912. IF: 1,346.

Molero JM, Moragas A, González López-Valcárcel B, Bjerrum L, Cots JM, Llor C. Reducing antibiotic prescribing for lower respiratory tract infections 6?years after a multifaceted intervention. Int. J. Clin. Pract.. 2019 May; 73(5):e13312. doi:10.1111/ijcp.13312. Epub 2019 Feb 06. PMID:30664320. IF: 2,613.

Moragas A, Molero JM, Bjerrum L, Llor C. General practitioners' opinions and perceptions about antibiotic use for respiratory tract infections in primary care. Aten Primaria. 2019;51(7):460-461. PMID:30922676. IF: 1,346.

Ruiz R, Moragas A, Trapero-Bertran M, Sisó A, Berenguera A, Oliva G, Borràs-Santos A, García-Sangenís A, Puig-Junoy J, Cots JM, Morros R, Mora T, Lanau-Roig A, Monfà R, Troncoso A, Abellana RM, Gálvez P, Medina-Perucha L, Bjerrum L, Amo I, Barragán N, Llor C. Effectiveness and cost-effectiveness of Improving clinicians' diagnostic and communication Skills on Antibiotic prescribing Appropriateness in patients with acute Cough in primary care in CATalonia (the ISAAC-CAT study): study protocol for a cluster randomised controlled trial. Trials. 2019 Dec 17;20(1):740. doi: 10.1186/s13063-019-3727-3. PubMed PMID: 31847912; PubMed Central PMCID: PMC6918568. IF: 1,975.

Indicators

Indicator

2019

Researchers with PhD

10

Total number of projects in which group members have participated

6

Total number of projects in which the PI of the project has belonged to the group

5

Total Funding

541.830,75€

Scientific publications in indexed journals

7

Total Impact factor

82,76

Nº of articles in Q1 journals

1

Q1 IF

70,67

Nº of articles in Q2 journals

3

Q2 IF

7,42

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