GREMPAL

Primary Care Research Group in Common Disorders of the Musculoskeletal System

The group resulted from the initiative of general practitioners from the primary care region Barcelona Litoral and Dreta de l'Eixample, in collaboration with the Bone and Joint Pathophysiology Research Unit of the IMIM-Parc de Salut Mar. From 2009 the group collaborates with the Epidemiology Unit of the Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford. The group aims to study the risk factors of the most common musculoskeletal disorders (osteoporosis and osteoarthritis) from a primary care perspective and the effectiveness of the treatments currently available.

The group participates in the following projects

PI: Reyes Reyes, Carlen. European Non-interventional Post Authorization Safety Study for romosozumab by the EU-ADR Alliance. Funding: Team-It Research S.L. Duration: 2020 - 2026

PI: Bundo Vidiella, Magdalena. Estudio transversal para analizar la epidemiología del pie diabético en los pacientes con diabetes mellitus tipo 2 con la base de datos SIDIAP. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Canivell Fusté, Silvia. Caracterización del riesgo fracturario en pacientes diabéticos mayores de 50 años tratados con SGLT2 inhibidores. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Reyes Reyes, Carlen. Estimating Short-Term and Long-Term Direct Economic Burden Associated with Osteoporotic Fracture. Funding: IQVIA World Publications Ltd. Duration: 2019 - 2021

PI: Prieto Alhambra, Daniel. A retrospective cohort study to assess modification of VKA and DOAC treatment effectiveness and safety among patients with atrial fibrillation in three countries. Funding: University of Oxford. Duration: 2019 - 2021

PI: Alfonso Boguña, Marta. Salut al dia: Efectivitat d'un programa de promoció de la salut en l'adolescència en l'àmbit escolar. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Carbonell Abella, Cristina. Avaluació de les infiltracions en Atenció Primària: estudi multicèntric. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Martínez Laguna, Daniel. Desarrollo y validación de una Escala de Riesgo de Fracturas Implementable en historia clínica electrónica (EPIC). Funding: Instituto de Salud Carlos III. Duration: 2018 - 2021

PI: Prieto Alhambra, Daniel. High blood eosinophil levels as independent risk factor of severe asthma exacerbations and mortality in adult patients with asthma. Funding: Synapse Research Management Partners, s.l. Duration: 2018 - 2020

PI: Reyes Reyes, Carlen. Opioid drug utilisation and comparative safety: a population-based cohort study. Funding: IDIAP Jordi Gol. Duration: 2018 - 2020

Group Publications

Ali MS, Berencsi K, Marinier K, Deltour N, Perez-Guthann S, Pedersen L, Rijnbeek P, Lapi F, Simonetti M, Reyes C, Van der Lei J, Sturkenboom M, Prieto-Alhambra D. Comparative cardiovascular safety of strontium ranelate and bisphosphonates: a multi-database study in 5 EU countries by the EU-ADR Alliance. Osteoporos Int. 2020 Dec; 31(12):2425-2438. doi:10.1007/s00198-020-05580-0. Epub 2020 Aug 05. PMID:32757044. IF: 3,864.

Berencsi K, Sami A, Ali MS, Marinier K, Deltour N, Perez-Gutthann S, Pedersen L, Rijnbeek P, Van der Lei J, Lapi F, Simonetti M, Reyes C, Sturkenboom MCJM, Prieto-Alhambra D. Correction to: Impact of risk minimisation measures on the use of strontium ranelate in Europe: a multi-national cohort study in 5 EU countries by the EU-ADR Alliance. Osteoporos Int. 2020 Apr; 31(4):799. doi:10.1007/s00198-020-05314-2. PMID:32025756. IF: 3,864.

Berencsi K, Sami A, Ali MS, Marinier K, Deltour N, Perez-Gutthann S, Pedersen L, Rijnbeek P, Van der Lei J, Lapi F, Simonetti M, Reyes C, Sturkenboom MCJM, Prieto-Alhambra D. Impact of risk minimisation measures on the use of strontium ranelate in Europe: a multi-national cohort study in 5 EU countries by the EU-ADR Alliance. Osteoporos Int. 2020 Apr; 31(4):721-755. doi:10.1007/s00198-019-05181-6. Epub 2019 Nov 06. PMID:31696274. IF: 3,864.

Lane JC, Butler KL, Poveda-Marina JL, Martinez-Laguna D, Reyes C, de Bont J, Javaid MK, Logue J, Compston JE, Cooper C, Duarte-Salles T, Furniss D, Prieto-Alhambra D. Preschool Obesity Is Associated With an Increased Risk of Childhood Fracture: A Longitudinal Cohort Study of 466,997 Children and Up to 11?Years of Follow-up in Catalonia, Spain. J Bone Miner Res. 2020 Jun; 35(6):1022-1030. doi:10.1002/jbmr.3984. Epub 2020 Apr 07. pmc:PMC7116071. PMID:32266748. IF: 5,854.

Palmer AJ, Poveda JL, Martinez-Laguna D, Reyes C, de Bont J, Silman A, Carr AJ, Duarte-Salles T, Prieto-Alhambra D. Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children. BMJ Open. 2020 Sep; 10(9):e036023. doi:10.1136/bmjopen-2019-036023. Epub 2020 Sep 17. PMID:32948552. IF: 2,496.

Prieto-Alhambra D, Turkiewicz A, Reyes C, Timpka S, Rosengren B, Englund M. Smoking and Alcohol Intake but Not Muscle Strength in Young Men Increase Fracture Risk at Middle Age: A Cohort Study Linked to the Swedish National Patient Registry. J. Bone Miner. Res. 2020 Mar; 35(3):498-504. doi:10.1002/jbmr.3917. Epub 2019 Dec 04. PMID:31714618. IF: 5,854.

Reyes C, Pons NA, Reñones CR, Gallisà JB, Val VA, Tebé C, Mateo GF. Association between serum ferritin and acute coronary heart disease: A population-based cohort study. Atherosclerosis. 2020 01; 293:69-74. doi:10.1016/j.atherosclerosis.2019.12.011. Epub 2019 Dec 13. PMID:31865056. IF: 3,919.

Skjødt MK, Khalid S, Ernst M, Rubin KH, Martinez-Laguna D, Delmestri A, Javaid MK, Cooper C, Libanati C, Toth E, Abrahamsen B, Prieto-Alhambra D. Secular trends in the initiation of therapy in secondary fracture prevention in Europe: a multi-national cohort study including data from Denmark, Catalonia, and the United Kingdom. Osteoporos Int. 2020 Aug; 31(8):1535-1544. doi:10.1007/s00198-020-05358-4. Epub 2020 Mar 17. pmc:PMC7360649. PMID:32185437. IF: 3,864.

Indicators

Indicator

2020

Researchers with PhD

8

Total number of projects in which group members have participated

10

Total number of projects in which the PI of the project has belonged to the group

5

Total Funding

684.372,97€

Scientific publications in indexed journals

8

Total Impact factor

33,58

Nº of articles in Q1 journals

3

Q1 IF

15,627

Nº of articles in Q2 journals

5

Q2 IF

17,952

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