GRENSSAP

Research Group in Primary Health Services

This group for research into primary health care services in Catalonia is made up of a team of researchers from IDIAP Jordi Gol who have been working on various lines of health service research for serveral years, and participate in important processes of evaluation and innovation in primary health care in Catalonia (evaluation of the objectives of the Catalan Health Service, the impact of electronic guidelines, the role of nurses in the care of acute problems, evaluation of a new model for emergency services, validation of Adjusted Clinical Groups®, etc.). Many of its members participated in the redIAPP network between 2003 and 2006 or in the IRYSS network (Investigation of Results and Health Services: G03/2020). In 2006 it again joined the redIAPP network. In 2009, it was accredited as an emergent group by the Department of Innovation, Universities and Business of the Catalan Generalitat. The general aim of the group is research into and systematic evaluation of general and specific aspects of the development and function of health services and their relationship with factors affecting health.

Group projects

PI: Duarte Salles, Talita. Obesity and cancer risk and survival: the role of co-morbidities. Funding: International Agency for Research on Cancer (IARC). Duration: 2020 - 2023

PI: Gómez Lumbreras, Ainhoa. Safety of medication use in pregnancy and breastfeeding: Demonstrating use of secondary data sources across Europe to study medications in pregnant women using the ConcePTION platform. Funding: UMC Utrecht (University Medical Center Utrecht). Duration: 2020 - 2022

PI: Sala Serra, Maria. CONCEPT-SURBCAN: uso de datos del mundo real para estudiar la efectividad y la eficiencia de la atención a supervivientes de cáncer de mama de larga duración. Funding: Instituto de Salud Carlos III. Duration: 2020 - 2022

PI: Bolíbar Ribas, Bonaventura. Cohorte DESVELA. Análisis del papel de las aptitudes personales como DEterminantes de la incidencia de morbilidad, eStilos de vida, calidad de Vida, uso de sErvicios y mortaLidAd. Funding: Instituto de Salud Carlos III. Duration: 2020 - 2022

PI: Violán Fors, Concepció. Construcción y validación de un Score predictivo de riesgo de institucionalización, ingresos hospitalarios y mortalidad, en mayores de 65 años con multimorbilidad y fragilidad. Funding: Instituto de Salud Carlos III. Duration: 2020 - 2022

PI: Llor Vilà, Carles. Effectiveness and cost-effectiveness of Improving clinicians' diagnostic and communication Skills on Antibiotic prescribing Appropriateness in patients with acute Cough in primary care in CATalonia. Funding: Fundacio La Marato de TV3. Duration: 2019 - 2022

PI: Morros Pedrós, Rosa. Evaluation of the effectiveness of pregnancy prevention programme (PPP) for oral retinoids (acitretin, alitreinoin, and isotretionoin): a European before-after drug utilization study (DUS) using secondary data. Funding: IQVIA Technology and Services AG. Duration: 2019 - 2022

PI: Duarte Salles, Talita. Body size and risk of development of 22 major cancers: Data from the Information System for the Development of Research in Primary Care collected on 6 million Catalans. Funding: WCRF NL Stichting Wereld Kanker Onderzoek Fonds. Duration: 2018 - 2022

PI: Llor Vilà, Carles. Efectividad del tratamiento antitusígeno, anticolinérgico y miel versus práctica habitual en adultos con bronquitis aguda no complicada. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2022

PI: Duarte Salles, Talita. The Information System for Research in Primary Care: EHDEN Data Partner. Funding: Erasmus universitair medisch centrum Rotterdam (EMC). Duration: 2020 - 2021

PI: Duarte Salles, Talita. Ranitidine and other histamine-H2-receptor antagonists - Drug Utilisation Study. Funding: Erasmus universitair medisch centrum Rotterdam (EMC). Duration: 2020 - 2021

PI: Berenguera Ossó, Anna. La atención primaria como promotora de la calidad de vida de pacientes con fibromialgia. Efectividad y coste-utilidad de una intervención compleja mediante ensayo clínico aleatorizado. Funding: Instituto de Salud Carlos III. Duration: 2019 - 2021

PI: Gómez Lumbreras, Ainhoa. Assessing drug exposure during pregnancy and breastfeeding and its outcomes in the offspring through a database cohort study. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Duarte Salles, Talita. Exploring the influence of cardiovascular disease risk at breast cancer diagnosis on systemic chemotherapy prescribing: A cross sectional study using Catalan databases. Funding: IDIAP Jordi Gol. Duration: 2019 - 2021

PI: Gómez Lumbreras, Ainhoa. Linaclotide Safety Study for the Assessment of Diarrhoea. Complications and Associated Risk Factors in Selected European Populations with IBS-C Study Protocol for Spain. Funding: Evidera, Inc. Duration: 2019 - 2021

PI: Duarte Salles, Talita. Knee and hip osteoarthritis and risk of cancer - register based epidemiology. Funding: IDIAP Jordi Gol. Duration: 2019 - 2021

PI: Bolíbar Ribas, Bonaventura. Impulsant l'excel·lència de la recerca en Atenció Primària i l'ús de Real World Data per millorar la salut de la població - GoEurope. Funding: Departament de Salut. Duration: 2019 - 2021

PI: Reyes Reyes, Carlen. Estimating Short-Term and Long-Term Direct Economic Burden Associated with Osteoporotic Fracture. Funding: IQVIA World Publications Ltd. Duration: 2019 - 2021

PI: Giner Soriano, Maria. Uso, efectividad y seguridad de los anticoagulantes orales directos en la prevención del ictus en fibrilación auricular: estudio de cohortes con datos procedentes de la historia clínica de atención primaria. Funding: IDIAP Jordi Gol. Duration: 2019 - 2021

PI: Duarte Salles, Talita. The Information System for Research in Primary Care: EHDEN Data Partner. Funding: ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM (EMC). Duration: 2019 - 2021

PI: Ponjoan Thans, Anna. Smart City Observatories implement REsilient Water Management. Funding: Fundació Institut Català de Recerca de l'Aigua (ICRA). Duration: 2019 - 2021

PI: Berenguera Ossó, Anna. La persona y su participación en la investigación. Las voces de la comunidad latinoamericana. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Berenguera Ossó, Anna. Percepciones acerca de la realización de actividad física en mujeres pakistaníes en el Raval ? una comparación entre primera y segunda generación. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Puente Baliarda, Diana. Síndrome metabólico y riesgo de cáncer: estudio caso-control con datos del Sistema de Información para el Desarrollo de la Investigación en Atención Primaria (SIDIAP) en Cataluña. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2021

PI: Fernández San Martin, Maria Isabel. Efectividad de una intervención grupal psicoeducativa realizada por enfermeras de Atención Primaria en pacientes con depresión y comorbilidad física. Funding: Instituto de Salud Carlos III. Duration: 2017 - 2021

PI: Duarte Salles, Talita. Utilisation and comparative safety of disease-modifying anti-rheumatic drugs (DMARDs) used for the treatment of rheumatoid arthritis: protocol for a multi-database real-world cohort study. Funding: IDIAP Jordi Gol. Duration: 2020

PI: Duarte Salles, Talita. Built environment in relation to the development of adult overweight and obesity: a mega-longitudinal study. Funding: IDIAP Jordi Gol. Duration: 2020

PI: Duarte Salles, Talita. Contaminación del aire, espacios verdes y cáncer de mama en Cataluña. Funding: IDIAP Jordi Gol. Duration: 2020

PI: Duarte Salles, Talita. Green Spaces and Air Pollution in relation to gastric cancer in Catalonia. A nested case-control study. Funding: IDIAP Jordi Gol. Duration: 2020

PI: Bolíbar Ribas, Bonaventura. Characterization and prediction of complications in front of the COVID19 pandemic. Funding: Departament de Salut. Duration: 2020

PI: Violán Fors, Concepció. Infección por SARS-CoV-2 en profesionales sanitarios: características poblacionales y respuesta serológica e inmune asociada al fenotipo de progresión. Funding: Departament de Salut. Duration: 2020

PI: Duarte Salles, Talita. COVID-19: Speeding access to COVID-19 patient data in Europe. Funding: University of Oxford. Duration: 2020

PI: Giner Soriano, Maria. Hiperpotassèmia en insuficiència renal. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2020

PI: Valencia -, Alfonso. Unveiling the molecular basis of disease co-occurrence: towards personalized comorbidity profiles. Funding: Barcelona Supercomputing Center (BSC-CNS). Duration: 2019 - 2020

PI: Giner Soriano, Maria. Safety and incidence of side effects in a cohort of postmenopausal women prescribed ospemifene relative to patients diagnosed with but not treated for vulvar and vaginal atrophy (VVA) and patients on selective oestrogen receptor modulators (SERMs) for oestrogen-deficiency conditions or breast cancer prevention: a post-authorisation safety study - Spain arm. Funding: Evidera, Inc. (GB668057994). Duration: 2018 - 2020

PI: Elices Armand-Ugon, Matilde. Interventional, randomised, open label, multi-centre, parallel-group, controlled study investigating the effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients. Funding: Consoricio Centro de Investigación Biomédica en RED (CIBER). Duration: 2018 - 2020

PI: Sala Serra, Maria. Comorbiditats i ús de serveis de salut en dones supervivents al càncer de mama. Funding: Fundació IMIM (Fundació Institut Mar d'Investigacions Mèdiques). Duration: 2018 - 2020

PI: Montero Pons, Laura. Avaluació qualitativa de la web Sexe Joves. Funding: Fundació Infermeria i Societat. Duration: 2018 - 2020

PI: - -, IP no primaria. Incidencia poblacional de la tentativa y de la repetición de tentativa de suicidio: evaluación del Código riesgo suicidio de Cataluña. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Rubio Valera, Maria. A non-interventional post-authorisation safety study (PASS) of vortioxetine in Europe An analysis of SIDIAP Database from Catalonia, Spain. Funding: H. Lundbeck A/S. Duration: 2018 - 2020

PI: Morros Pedrós, Rosa. Uso de la Medicación psicotrópica en niños y adolescentes en Cataluña. Estudio de cohortes 2007-2017 con real world data procedentes de la historia electrónica de atención primaria. Funding: Fundació Academia Ciencies Mediques de Catalunya I de Balears (L'Acadèmia). Duration: 2018 - 2020

PI: Morros Pedrós, Rosa. Uso de la Medicación psicotrópica en niños y adolescentes en Cataluña. Estudio de cohortes 2007-2017 con real world data procedentes de la historia electrónica de atención primaria. Funding: Departament de Salut. Duration: 2018 - 2020

PI: Duarte Salles, Talita. The impact of comorbidities on cancer detection and survival (ComoCanS). Funding: International Agency for Research on Cancer (IARC). Duration: 2018 - 2020

PI: Duarte Salles, Talita. Relación entre el metabolismo de la glucosa y la enfermedad de Parkinson. Estudio epidemiológico y búsqueda de asociaciones metabólicas. Funding: Fundació Clínic per a la Recerca Biomèdica. Duration: 2018 - 2020

PI: Puig Ribera, Anna. Sentarse menos y moverse más en el trabajo: Impacto de un programa mHealth sobre el control glucémico y perfil antropométrico en personal de oficina con DT2. Ensayo Clínico Aleatorizado. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Montero Alía, Pilar. Seguiment a llarg termini del balanç postural i caigudes en la cohort de pacients de l'estudi E Wii. Funding: ICS - Institut Català de la Salut. Duration: 2018 - 2020

PI: Morros Pedrós, Rosa. Diagnósticos en Patología Psiquiátrica Infantil (PEPSICAT-DX). Funding: Departament de Salut. Duration: 2018 - 2020

PI: Duarte Salles, Talita. Urban environment and childhood obesity in Catalonia (ECHOCAT). Funding: Fundacio La Marato de TV3. Duration: 2017 - 2020

PI: Costa Pinel, Bernardo. Diabetes Prevention - Translating a feasible and cost-effective lifestyle intervention into primary care to reduce the social burden of type 2 diabetes. Funding: Fundacio La Marato de TV3. Duration: 2016 - 2020

The group participates in the following projects

PI: Violán Fors, Concepció. TADIA_MED. Funding: Universitat Politècnica de Catalunya (UPC). Duration: 2020 - 2023

PI: Morros Pedrós, Rosa. Características sociodemográficas, clínicas y farmacológicas asociadas con el pronóstico en pacientes con infección por SARS-CoV-2. Funding: IDIAP Jordi Gol. Duration: 2020 - 2022

PI: Duarte Salles, Talita. Musculoskeletal adverse outcomes after treatment with aromatase inhibitors for breast cancer: a SIDIAP-OHDSI based cohort study. Funding: University of Oxford. Duration: 2020 - 2022

PI: Duarte Salles, Talita. Use of hydrochlorothiazide and risk of skin cancer. Funding: IDIAP Jordi Gol. Duration: 2020 - 2022

PI: Duarte Salles, Talita. Residential outdoor play spaces and children's diagnosed mental and behavioural disorders: the role of individual and area-level socio economic characteristics. Funding: IDIAP Jordi Gol. Duration: 2020 - 2022

PI: Aragón Pérez, María. vACCine covid-19 monitoring readinESS (ACCESS). Funding: UMC Utrecht (University Medical Center Utrecht). Duration: 2020 - 2022

PI: Falguera Puig, Gemma. Pregnancy Health in Epidemiological Crise Covid19 (PreHEpic19). Funding: ICS - Institut Català de la Salut. Duration: 2020 - 2022

PI: Ricci Cabello, Ignacio. Desarrollo y evaluación de la efectividad, coste-efectividad e implementación de una intervención digital multicomponente de baja intensidad para prevenir diabetes mellitus tipo 2 desde el ámbito de la Atención Primaria: Estudio PREDIABETEXT. Funding: Fundacio Investigacio Sanitaria de les Illes Balears (IdISba). Duration: 2019 - 2022

PI: Queiroga Gonçalves, Alessandra. Evaluación cualitativa de la implementación de una intervención compleja para el cribado de población inmigrante en el ámbito de la atención primaria. Funding: Consorci d'Atenció Primària de Salut Barcelona Esquerre (CAPSBE). Duration: 2019 - 2022

PI: Morros Pedrós, Rosa. Ensayo clínico doble ciego, aleatorizado, controlado con placebo, para evaluar la eficacia del complemento alimentario Manremyc® para evitar la infección por SARS-CoV-2. Funding: Laboratorio Reig Jofré, S.A. Duration: 2020 - 2021

PI: Magallón Botaya, Rosa. Variables pronósticas, recursos consumidos y coste en atención primaria de pacientes con COVID-19. Funding: Instituto de Salud Carlos III. Duration: 2020 - 2021

PI: Duarte Salles, Talita. OHDSI: Comparative risk of the incident cancer between histamine-2 receptor antagonists. Funding: . Duration: 2020 - 2021

PI: Violán Fors, Concepció. Genetic Evaluation of Multimorbidity towards INdividualisation of Interventions. Funding: University of Exeter . Duration: 2020 - 2021

PI: - -, IP no primaria. Monitoring of SARS-CoV-2 seroprevalence among primary health care patients as a sentinel COVID-19 surveillance in Barcelona health region. Funding: Departament de Salut. Duration: 2020 - 2021

PI: Berenguera Ossó, Anna. Impacto social generado en la población durante y después del confinamiento aplicado como medida de prevención y control del SARS-CoV-2 en Brasil, Chile, Ecuador, España, México y Perú. Funding: Departament de Salut. Duration: 2020 - 2021

PI: Violán Fors, Concepció. COVID-19, perfil inmunológico de riesgo (adscrito al proyecto presentado por el VHIR IP R Pujol-Borrell). Funding: Instituto de Salud Carlos III. Duration: 2020 - 2021

PI: Duarte Salles, Talita. Cancer risk and mortality after bariatric surgery: a protocol for a multi-database cohort study. Funding: IDIAP Jordi Gol. Duration: 2020

PI: - -, IP no primaria. Identificación y caracterización de la respuesta inmune T protectora frente a SARS-CoV-2: Guiando con éxito el diseño de vacunas. Funding: Instituto de Salud Carlos III. Duration: 2020

PI: Cabezas Peña, Maria del Carmen. La salut en temps de confinament pel coronavirus. Funding: ICS - Institut Català de la Salut. Duration: 2020

PI: Llor Vilà, Carles. Community acquired acute respiratory tract infection (CA-ARTI) in community care in Europe: point prevalence audit study (PPAS) of presentation and management. Funding: University of Oxford. Duration: 2019 - 2020

Group Publications

Braeye T, Emborg HD, Llorente-García A, Huerta C, Martín-Merino E, Duarte-Salles T, Danieli G, Tramontan L, Weibel D, McGee C, Villa M, Gini R, Lehtinen M, Titievsky L, Sturkenboom M. Age-specific vaccination coverage estimates for influenza, human papillomavirus and measles containing vaccines from seven population-based healthcare databases from four EU countries - The ADVANCE project. Vaccine. 2020 Apr; 38(16):3243-3254. doi:10.1016/j.vaccine.2020.02.082. Epub 2020 Mar 12. PMID:32171573. IF: 3,143.

Cánovas Zaldúa Y, Casabella Abril B, Martín Cantera C, González García F, Moreno Escribá S, Del Val García JL. [Evaluation of a training model for health professionals in the care of critical patients: AIPCAP Study]. Aten Primaria. 2020 Mar; 52(3):151-158. doi:10.1016/j.aprim.2018.08.009. Epub 2019 Jan 10. Spanish. pmc:PMC7063162. PMID:30638697. IF: 1,087.

de Bont J, Díaz Y, Casas M, García-Gil M, Vrijheid M, Duarte-Salles T. Time Trends and Sociodemographic Factors Associated With Overweight and Obesity in Children and Adolescents in Spain. JAMA Netw Open. 2020 Mar 2;3(3):e201171. doi: 10.1001/jamanetworkopen.2020.1171. PubMed PMID: 32186743.

Dodd C, de Ridder M, Weibel D, Mahaux O, Haguinet F, de Smedt T, de Lusignan S, McGee C, Duarte-Salles T, Emborg HD, Huerta C, Martín-Merino E, Picelli G, Berencsi K, Danieli G, Sturkenboom M. ADVANCE system testing: Estimating the incidence of adverse events following pertussis vaccination in healthcare databases with incomplete exposure data. Vaccine. 2020 Apr; doi:10.1016/j.vaccine.2020.03.050. Epub 2020 Apr 09. PMID:32280043. IF: 3,143.

Giner-Soriano M, Casajuana M, Roso-Llorach A, Vedia C, Morros R. [Effectiveness, safety and costs of stroke prevention in non-valvular auricular fibrillation. Study of cohorts matched by Propensity score]. Aten Primaria. 2020 Mar; 52(3):176-184. doi:10.1016/j.aprim.2019.06.002. Epub 2019 Sep 21. Spanish. pmc:PMC7063152. PMID:31551166. IF: 1,087.

Gini R, Dodd CN, Bollaerts K, Bartolini C, Roberto G, Huerta-Alvarez C, Martín-Merino E, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Becker BFH, Switzer C, Gandhi-Banga S, Bauwens J, van der Maas NAT, Spiteri G, Sdona E, Weibel D, Sturkenboom M. Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project. Vaccine. 2020 12; 38 Suppl 2:B56-B64. doi:10.1016/j.vaccine.2019.07.045. Epub 2019 Oct 31. PMID:31677950. IF: 3,143.

Gómez-Lumbreras A, Vedia Urgell C, Morros Pedrós R. [Research works and ethics committees in primary care]. Aten Primaria. 2020 02; 52(2):127-128. doi:10.1016/j.aprim.2019.06.008. Epub 2019 Aug 05. Spanish. pmc:PMC7025966. PMID:31395415. IF: 1,087.

Ibáñez-Sanz G, Guinó E, Pontes C, Morros R, de la Peña-Negro LC, Quijada-Manuitt MÁ, Moreno V. Risk of colorectal cancer in users of bisphosphonates: analysis of population-based electronic health records. Eur. J. Epidemiol. 2020 Jan; 35(1):37-48. doi:10.1007/s10654-019-00584-5. Epub 2019 Nov 16. PMID:31734885. IF: 7,135.

Jacques-Aviñó C, Pons-Vigués M, Mcghie JE, Rodríguez-Giralt I, Medina-Perucha L, Mahtani-Chugani V, Pujol-Ribera E, Berenguera Ossó A. Public participation in research projects: ways of creating collective knowledge in health. Gac Sanit. 2020 Mar; 34(2):200-203. doi:10.1016/j.gaceta.2019.08.010. Epub 2019 Nov 27. Spanish. PMID:31785893. IF: 1,564.

Lane JC, Butler KL, Poveda-Marina JL, Martinez-Laguna D, Reyes C, de Bont J, Javaid MK, Logue J, Compston JE, Cooper C, Duarte-Salles T, Furniss D, Prieto-Alhambra D. Preschool Obesity Is Associated With an Increased Risk of Childhood Fracture: A Longitudinal Cohort Study of 466,997 Children and Up to 11?Years of Follow-up in Catalonia, Spain. J Bone Miner Res. 2020 Jun; 35(6):1022-1030. doi:10.1002/jbmr.3984. Epub 2020 Apr 07. pmc:PMC7116071. PMID:32266748. IF: 5,854.

Lapena C, Continente X, Sánchez Mascuñano A, Pons-Vigués M, Pujol-Ribera E, Lopez MJ. Qualitative evaluation of a community-based intervention to reduce social isolation among older people in disadvantaged urban areas of Barcelona. Health Soc Care Community. 2020;28(5):1488-1503. PMID:32185842. IF: 2,050.

Marengoni A, Roso-Llorach A, Vetrano DL, Fernández-Bertolín S, Guisado-Clavero M, Violán C, Calderón-Larrañaga A. Patterns of Multimorbidity in a Population-Based Cohort of Older People: Sociodemographic, Lifestyle, Clinical, and Functional Differences. J. Gerontol. A Biol. Sci. Med. Sci. 2020 Mar; 75(4):798-805. doi:10.1093/gerona/glz137. PMID:31125398. IF: 5,236.

Newby D, Prieto-Alhambra D, Duarte-Salles T, Ansell D, Pedersen L, van der Lei J, Mosseveld M, Rijnbeek P, James G, Alexander M, Egger P, Podhorna J, Stewart R, Perera G, Avillach P, Grosdidier S, Lovestone S, Nevado-Holgado AJ. Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study. Alzheimers Res Ther. 2020 Apr; 12(1):38. doi:10.1186/s13195-020-00606-5. Epub 2020 Apr 06. PMID:32252806. IF: 6,116.

Planas-Campmany C, Zabaleta-Del-Olmo E, Violán C, Pérez-Sánchez G, Navas-Palacios JJ. Profile of Innovative Ideas Recorded by Nurses in an Ideas Bank of a Corporate Virtual Community of Open Innovation: A Cross-Sectional Study. J Nurs Scholarsh. 2020 Apr; doi:10.1111/jnu.12559. Epub 2020 Apr 28. PMID:32346930. IF: 2,655.

Sturkenboom M, Braeye T, van der Aa L, Danieli G, Dodd C, Duarte-Salles T, Emborg HD, Gheorghe M, Kahlert J, Gini R, Huerta C, Martín-Merino E, McGee C, de Lusignan S, Picelli G, Roberto G, Tramontan L, Villa M, Weibel D, Titievsky L. ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations. Vaccine. 2020 Feb; doi:10.1016/j.vaccine.2020.01.100. Epub 2020 Feb 12. PMID:32061385. IF: 3,143.

Urpí-Fernández AM, Zabaleta-Del-Olmo E, Tomás-Sábado J, Tambo-Lizalde E, Roldán-Merino JF. [Adapting and validating a questionnaire to measure the self-care practices in healthy child population residing in Spain]. Aten Primaria. 2020 May; 52(5):297-306. doi:10.1016/j.aprim.2018.10.004. Epub 2019 Mar 27. Spanish. pmc:PMC7231858. PMID:30926294. IF: 1,087.

Weibel D, Dodd C, Mahaux O, Haguinet F, De Smedt T, Duarte-Salles T, Picelli G, Tramontan L, Danieli G, Correa A, McGee C, Martín-Merino E, Huerta-Alvarez C, Berencsi K, Emborg HD, Bollaerts K, Bauchau V, Titievsky L, Sturkenboom M. ADVANCE system testing: Can safety studies be conducted using electronic healthcare data? An example using pertussis vaccination. Vaccine. 2020 12; 38 Suppl 2:B38-B46. doi:10.1016/j.vaccine.2019.06.040. Epub 2019 Oct 31. PMID:31677946. IF: 3,143.

The group participates in the following publications

ane JCE, Weaver J, Kostka K, Duarte-Salles T, Abrahao MTF, Alghoul H, Alser O, Alshammari TM, Biedermann P, Banda JM, Burn E, Casajust P, Conover MM, Culhane AC, Davydov A, DuVall SL, Dymshyts D, Fernandez-Bertolin S, Fiter K, Hardin J, Hester L, Hripcsak G, Kaas-Hansen BS, Kent S, Khosla S, Kolovos S, Lambert CG, van der Lei J, Lynch KE, Makadia R, Margulis AV, Matheny ME, Mehta P, Morales DR, Morgan-Stewart H, Mosseveld M, Newby D, Nyberg F, Ostropolets A, Park RW, Prats-Uribe A, Rao GA, Reich C, Reps J, Rijnbeek P, Sathappan SMK, Schuemie M, Seager S, Sena AG, Shoaibi A, Spotnitz M, Suchard MA, Torre CO, Vizcaya D, Wen H, de Wilde M, Xie J, You SC, Zhang L, Zhuk O, Ryan P, Prieto-Alhambra D; OHDSI-COVID-19 consortium. Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study. Lancet Rheumatol. 2020 Nov; 2(11):e698-e711. doi:10.1016/S2665-9913(20)30276-9. Epub 2020 Aug 21. pmc:PMC7442425. PMID:32864627.

Arfuch VM, Caballol Angelats R, Aguilar Martín C, Carrasco-Querol N, Sancho Sol MC, González Serra G, Fusté Anguera I, Gonçalves AQ, Berenguera A. Assessing the benefits on quality of life of a multicomponent intervention for fibromyalgia syndrome in primary care: patients' and health professionals' appraisals: a qualitative study protocol. BMJ Open. 2020 Nov 11;10(11):e039873. doi: 10.1136/bmjopen-2020-039873. IF: 2,496.

Berenguera A, Coma N, Carmona V, Pons M, Pujol E, Medina L, Jacques C, Moix J. Vivir con artrosis de rodilla es como. . . La utilidad de las metáforas para entender la experiencia vital. Aten Primaria. 2020;2(1-2):100041-100041. IF: 1,087.

Brotons M, Monfil L, Roura E, Duarte-Salles T, Casabona J, Urbiztondo L, Cabezas C, Bosch FX, de Sanjosé S, Bruni L. Impact of a single-age cohort human papillomavirus vaccination strategy in Catalonia, Spain: Population-based analysis of anogenital warts in men and women. Prev Med. 2020 Jun; doi:10.1016/j.ypmed.2020.106166. Epub 2020 Jun 18. PMID:32565118. IF: 3,788.

Burn E, You SC, Sena AG, Kostka K, Abedtash H, Abrahão MTF, Alberga A, Alghoul H, Alser O, Alshammari TM, Aragon M, Areia C, Banda JM, Cho J, Culhane AC, Davydov A, DeFalco FJ, Duarte-Salles T, DuVall S, Falconer T, Fernandez-Bertolin S, Gao W, Golozar A, Hardin J, Hripcsak G, Huser V, Jeon H, Jing Y, Jung CY, Kaas-Hansen BS, Kaduk D, Kent S, Kim Y, Kolovos S, Lane JCE, Lee H, Lynch KE, Makadia R, Matheny ME, Mehta PP, Morales DR, Natarajan K, Nyberg F, Ostropolets A, Park RW, Park J, Posada JD, Prats-Uribe A, Rao G, Reich C, Rho Y, Rijnbeek P, Schilling LM, Schuemie M, Shah NH, Shoaibi A, Song S, Spotnitz M, Suchard MA, Swerdel JN, Vizcaya D, Volpe S, Wen H, Williams AE, Yimer BB, Zhang L, Zhuk O, Prieto-Alhambra D, Ryan P. Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study. Nat Commun. 2020 10; 11(1):5009. doi:10.1038/s41467-020-18849-z. Epub 2020 Oct 06. PMID:33024121. IF: 12,121.

Burn E, You SC, Sena AG, Kostka K, Abedtash H, Abrahão MTF, Alberga A, Alghoul H, Alser O, Alshammari TM, Areia C, Banda JM, Cho J, Culhane AC, Davydov A, DeFalco FJ, Duarte-Salles T, DuVall S, Falconer T, Gao W, Golozar A, Hardin J, Hripcsak G, Huser V, Jeon H, Jing Y, Jung CY, Kaas-Hansen BS, Kaduk D, Kent S, Kim Y, Kolovos S, Lane JCE, Lee H, Lynch KE, Makadia R, Matheny ME, Mehta P, Morales DR, Natarajan K, Nyberg F, Ostropolets A, Park RW, Park J, Posada JD, Prats-Uribe A, Rao G, Reich C, Rho Y, Rijnbeek P, Sathappan SMK, Schilling LM, Schuemie M, Shah NH, Shoaibi A, Song S, Spotnitz M, Suchard MA, Swerdel JN, Vizcaya D, Volpe S, Wen H, Williams AE, Yimer BB, Zhang L, Zhuk O, Prieto-Alhambra D, Ryan P. An international characterisation of patients hospitalised with COVID-19 and a comparison with those previously hospitalised with influenza. medRxiv. 2020 Apr; doi:10.1101/2020.04.22.20074336. Epub 2020 Apr 25. pmc:PMC7239064. PMID:32511443.

Cabrera-Bean M, Pereira Dos Santos VJ, Roso-Llorach A, Fernandez-Bertolin S, Vidal J, Violan C. Autoencoders for health improvement by compressing the set of patient features. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul; 2020:5917-5920. doi:10.1109/EMBC44109.2020.9176209. PMID:33019321.

Cairns I, Lindsay K, Dalbeth N, Díaz-Torné C, Antònia Pou M, Rodríguez Diez B, Pujol-Ribera E, Panter C, Arbuckle R, Tatlock S, Taylor WJ. The impact of gout as described by patients, using the lens of The International Classification of Functioning, Disability and Health (ICF): a qualitative study. BMC Rheumatol. 2020 ; 4:50. doi:10.1186/s41927-020-00147-2. Epub 2020 Aug 12. pmc:PMC7422533. PMID:32832854.

Checa C, Medina-Perucha L, Muñoz MÁ, Verdú-Rotellar JM, Berenguera A. Living with advanced heart failure: A qualitative study. PLoS One. 2020 ; 15(12):e0243974. doi:10.1371/journal.pone.0243974. Epub 2020 Dec 14. pmc:PMC7735582. PMID:33315935. IF: 2,740.

de Bont J, Hughes R, Tilling K, Díaz Y, de Castro M, Cirach M, Fossati S, Nieuwenhuijsen M, Duarte-Salles T, Vrijheid M. Early life exposure to air pollution, green spaces and built environment, and body mass index growth trajectories during the first 5 years of life: A large longitudinal study. Environ. Pollut. 2020 Jul; 266(Pt 3):115266. doi:10.1016/j.envpol.2020.115266. Epub 2020 Jul 28. PMID:32745901. IF: 6,793.

Duarte-Salles T, Vizcaya D, Pistillo A, Casajust P, Sena AG, Lai LYH, Prats-Uribe A, Ahmed WU, Alshammari TM, Alghoul H, Alser O, Burn E, You SC, Areia C, Blacketer C, DuVall S, Falconer T, Fernandez-Bertolin S, Fortin S, Golozar A, Gong M, Tan EH, Huser V, Iveli P, Morales DR, Nyberg F, Posada JD, Recalde M, Roel E, Schilling LM, Shah NH, Shah K, Suchard MA, Zhang L, Williams AE, Reich CG, Kostka K, Prieto-Alhambra D. Baseline characteristics, management, and outcomes of 55,270 children and adolescents diagnosed with COVID-19 and 1,952,693 with influenza in France, Germany, Spain, South Korea and the United States: an international network cohort study. medRxiv. 2020 Oct; doi:10.1101/2020.10.29.20222083. Epub 2020 Oct 30. pmc:PMC7605587. PMID:33140074.

Fernández-Álvarez MDM, Martín-Payo R, Zabaleta-Del-Olmo E, García-García R, Cuesta-Izquierdo M, González-Méndez X. [Assessment of diet quality and physical activity of soccer players aged 13 to 16, from the Principality of Asturias, Spain]. An Pediatr (Engl Ed). 2020 Jul; doi:10.1016/j.anpedi.2020.05.024. Epub 2020 Jul 21. Spanish. PMID:32709526. IF: 1,313.

García R, Manresa JM, Torán P, Moreno N, Sabaté V, Romero M, Moreno E, Pera G, Montellà N, Seda G, Violán C, Bonet JM, Prat NP. Descriptive study of the health service workers of a Primary Care Department confined by Covid-19. Rev Esp Salud Publica. 2020;94(e202009106):e1-11. PMID:32880381. IF: 0,746.

Giner-Soriano M, Cortes J, Gomez-Lumbreras A, Prat-Vallverdú O, Quijada-Manuitt MA, Morros R. The use and adherence of oral anticoagulants in Primary Health Care in Catalunya, Spain: A real-world data cohort study. Aten Primaria. 2020 Oct;52(8):529-538. doi: 10.1016/j.aprim.2020.05.016. Epub 2020 Aug 9. PMID: 32788057; PMCID: PMC7505898. IF: 1,087.

Gómez-Gómez I, Moreno-Peral P, López T, Clavería A, Oliván B, Marti R, Llobera J, Maderuelo-Fernández JA, Motrico E. Multiple risk behaviour intervention to prevent depression in primary care. Br J Gen Pract. 2020 Jun; 70(suppl 1). doi:10.3399/bjgp20X711677. PMID:32554688. IF: 4,190.

Hernández Z, Dalmau MR, Aguilar C, Queiroga A, Casajuana M, Fernández J, Rodriguez D, Forcadell E, Carrasco N, Pepió JM. Cost-effectiveness of direct oral anticoagulants versus vitamin K antagonist in atrial fibrillation: A study protocol using Real-World Data from Catalonia (FantasTIC Study). Medicine (Baltimore). 2020;36(99):1-7. PMID:32899067. IF: 1,552.

Ibáñez-Sanz G, Guinó E, Morros R, Quijada-Manuitt MÁ, de la Peña-Negro LC, Moreno V. Chondroitin Sulphate and Glucosamine Use Depend on Nonsteroidal Anti-inflammatory Drug Use to Modify the Risk for Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2020 Sep; 29(9):1809-1816. doi:10.1158/1055-9965.EPI-19-1051. Epub 2020 Jul 10. PMID:32651216. IF: 4,344.

Jacques-Aviñó C, López-Jiménez T, Medina-Perucha L, de Bont J, Gonçalves AQ, Duarte-Salles T, Berenguera A. Gender-based approach on the social impact and mental health in Spain during COVID-19 lockdown: a cross-sectional study. BMJ Open. 2020 11; 10(11):e044617. doi:10.1136/bmjopen-2020-044617. Epub 2020 Nov 24. pmc:PMC7688440. PMID:33234664. IF: 2,496.

León-Salas B, Zabaleta-Del-Olmo E, Llobera J, Bolíbar-Ribas B, López-Jiménez T, Casajuana-Closas M, Esteva M. Health status, lifestyle habits, and perceived social support in long-term cancer survivors: a cross-sectional study. BMC Res Notes. 2020 Aug; 13(1):376. doi:10.1186/s13104-020-05218-8. Epub 2020 Aug 08. pmc:PMC7414741. PMID:32771042.

Lopez-Dicastillo O, Zabaleta-Del-Olmo E, Mujika A, Antoñanzas-Baztán E, Hernantes N, Pumar-Méndez MJ. "Missed nursing care" in health promotion: Raising awareness [published online ahead of print, 2020 Apr 6]. J Nurs Manag. 2020;10.1111/jonm.13016. doi:10.1111/jonm.13016 IF: 2,243.

Martin-Cantera C, Sanmartín JMI, Martínez AF, Lorenzo CM, Cohen VB, Jiménez MLC, Pérez-Teijón SC, Osca JARI, García RC, Fernández JL, Domenech MAG, Navascues MAM, Chaves ES, Ibañez MLR, Rubio VG, Rayo SM, Otero BM, Lopez LG, Guillem FC, Fuente FM, Ruiz DB, Rodríguez AIH, Caballero JDG, Moreno CB, Pubil MP, Grau ML. Good practice regarding smoking cessation management in Spain: Challenges and opportunities for primary care physicians and nurses. Tob Prev Cessat. 2020 ; 6:55. doi:10.18332/tpc/126630. Epub 2020 Sep 21. pmc:PMC7552853. PMID:33083683.

Medina L, Jacques C, López T, Berenguera A. Menstrual health and period poverty among young people who menstruate in the Barcelona metropolitan area (Spain): protocol of a mixed-methods study. BMJ Open. 2020;10:1-8. PMID:32727738. IF: 2,496.

Medina-Perucha L, García-Sangenís A, Moragas A, Gálvez-Hernández P, Cots JM, Lanau-Roig A, Borràs A, Amo I, Monfà R, Llor C, Berenguera A. Autonomy, power dynamics and antibiotic use in primary healthcare: A qualitative study. PLoS One. 2020 ; 15(12):e0244432. doi:10.1371/journal.pone.0244432. Epub 2020 Dec 18. PMID:33338078. IF: 2,740.

Morales DR, Conover MM, You SC, Pratt N, Kostka K, Duarte-Salles T, Fernández-Bertolín S, Aragón M, DuVall SL, Lynch K, Falconer T, van Bochove K, Sung C, Matheny ME, Lambert CG, Nyberg F, Alshammari TM, Williams AE, Park RW, Weaver J, Sena AG, Schuemie MJ, Rijnbeek PR, Williams RD, Lane JCE, Prats-Uribe A, Zhang L, Areia C, Krumholz HM, Prieto-Alhambra D, Ryan PB, Hripcsak G, Suchard MA. Renin-angiotensin system blockers and susceptibility to COVID-19: a multinational open science cohort study. medRxiv. 2020 Jun; doi:10.1101/2020.06.11.20125849. Epub 2020 Jun 12. pmc:PMC7310640. PMID:32587982.

Morales DR, Conover MM, You SC, Pratt N, Kostka K, Duarte-Salles T, Fernández-Bertolín S, Aragón M, DuVall SL, Lynch K, Falconer T, van Bochove K, Sung C, Matheny ME, Lambert CG, Nyberg F, Alshammari TM, Williams AE, Park RW, Weaver J, Sena AG, Schuemie MJ, Rijnbeek PR, Williams RD, Lane JCE, Prats-Uribe A, Zhang L, Areia C, Krumholz HM, Prieto-Alhambra D, Ryan PB, Hripcsak G, Suchard MA. Renin-angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis. Lancet Digit Health. 2020 Dec; doi:10.1016/S2589-7500(20)30289-2. Epub 2020 Dec 17. PMID:33342753.

Mortier P, Vilagut G, Puértolas Gracia B, De Inés Trujillo A, Alayo Bueno I, Ballester Coma L, Blasco Cubedo MJ, Cardoner N, Colls C, Elices M, Garcia-Altes A, Gené Badia M, Gómez Sánchez J, Martín Sánchez M, Morros R, Prat Pubill B, Qin P, Mehlum L, Kessler RC, Palao D, Pérez Sola V, Alonso J; CODIRISC Epidemiology Study Group. Catalonia Suicide Risk Code Epidemiology (CSRC-Epi) study: protocol for a population-representative nested case-control study of suicide attempts in Catalonia, Spain. BMJ Open. 2020 07; 10(7):e037365. doi:10.1136/bmjopen-2020-037365. Epub 2020 Jul 12. pmc:PMC7359191. PMID:32660952. IF: 2,496.

Palmer AJ, Poveda JL, Martinez-Laguna D, Reyes C, de Bont J, Silman A, Carr AJ, Duarte-Salles T, Prieto-Alhambra D. Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children. BMJ Open. 2020 Sep; 10(9):e036023. doi:10.1136/bmjopen-2019-036023. Epub 2020 Sep 17. PMID:32948552. IF: 2,496.

Palomero L, Galván-Femenía I, de Cid R, Espín R, Barnes DR, Cimba , Blommaert E, Gil-Gil M, Falo C, Stradella A, Ouchi D, Roso-Llorach A, Violan C, Peña-Chilet M, Dopazo J, Extremera AI, García-Valero M, Herranz C, Mateo F, Mereu E, Beesley J, Chenevix-Trench G, Roux C, Mak T, Brunet J, Hakem R, Gorrini C, Antoniou AC, Lázaro C, Pujana MA. Immune Cell Associations with Cancer Risk. iScience. 2020 Jun; 23(7):101296. doi:10.1016/j.isci.2020.101296. Epub 2020 Jun 20. PMID:32622267. IF: 4,447.

Parody E, Rubio M, Gómez A, Casajuana M, Carbonell C, Aznar I. Economic Evaluations Informed Exclusively by Real World Data: A Systematic Review. Int J Environ Res Public Health. 2020;17:E1171-E1171. PMID:32059593. IF: 2,849.

Perera G, Rijnbeek PR, Alexander M, Ansell D, Avillach P, Duarte-Salles T, Gordon MF, Lapi F, Mayer MA, Pasqua A, Pedersen L, van Der Lei J, Visser PJ, Stewart R. Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case-control study using European electronic health records. BMJ Open. 2020 Nov; 10(11):e038753. doi:10.1136/bmjopen-2020-038753. Epub 2020 Nov 14. pmc:PMC7668358. PMID:33191253. IF: 2,496.

Prieto Alhambra, D., Fernandez-Bertolin, S., Prats-Uribe, A., Recalde, M., Tebé, C., Aragon, M., Burn, E., Roel, E., & Duarte-Salles, T. The natural history of symptomatic COVID-19: a multi-state model of the first wave in Catalonia, including 102,002 outpatient diagnoses, 16,901 hospitalisations, and 5,273 COVID-19 deaths among 5,586,521 people. Nat Commun. 2020 IF: 12,121.

Stepien M, Keski-Rahkonen P, Kiss A, Robinot N, Duarte-Salles T, Murphy N, Perlemuter G, Viallon V, Tjønneland A, Rostgaard-Hansen AL, Dahm CC, Overvad K, Boutron-Ruault MC, Mancini FR, Mahamat-Saleh Y, Aleksandrova K, Kaaks R, Kühn T, Trichopoulou A, Karakatsani A, Panico S, Tumino R, Palli D, Tagliabue G, Naccarati A, Vermeulen RCH, Bueno-de-Mesquita HB, Weiderpass E, Skeie G, Ramón Quirós J, Ardanaz E, Mokoroa O, Sala N, Sánchez MJ, Huerta JM, Winkvist A, Harlid S, Ohlsson B, Sjöberg K, Schmidt JA, Wareham N, Khaw KT, Ferrari P, Rothwell JA, Gunter M, Riboli E, Scalbert A, Jenab M. Metabolic perturbations prior to hepatocellular carcinoma diagnosis: Findings from a prospective observational cohort study. Int J Cancer. 2021 Feb; 148(3):609-625. doi:10.1002/ijc.33236. Epub 2020 Aug 28. PMID:32734650. IF: 5,145.

Tan EH, Sena AG, Prats-Uribe A, You SC, Ahmed WU, Kostka K, Reich C, Duvall SL, Lynch KE, Matheny ME, Duarte-Salles T, Bertolin SF, Hripcsak G, Natarajan K, Falconer T, Spotnitz M, Ostropolets A, Blacketer C, Alshammari TM, Alghoul H, Alser O, Lane JCE, Dawoud DM, Shah K, Yang Y, Zhang L, Areia C, Golozar A, Relcade M, Casajust P, Jonnagaddala J, Subbian V, Vizcaya D, Lai LY, Nyberg F, Morales DR, Posada JD, Shah NH, Gong M, Vivekanantham A, Abend A, Minty EP, Suchard M, Rijnbeek P, Ryan PB, Prieto-Alhambra D. Characteristics, outcomes, and mortality amongst 133,589 patients with prevalent autoimmune diseases diagnosed with, and 48,418 hospitalised for COVID-19: a multinational distributed network cohort analysis. medRxiv. 2020 Nov; doi:10.1101/2020.11.24.20236802. Epub 2020 Nov 27. pmc:PMC7709171. PMID:33269355.

Travier N, Fu M, Romaguera A, Martín-Cantera C, Fernández E, Vidal C, Garcia M; LUCAPREV research group. 6-Year Risk of Developing Lung Cancer in Spain: Analysis by Autonomous Communities. Arch Bronconeumol. 2020 May; doi:10.1016/j.arbres.2020.03.022. Epub 2020 May 10. PMID:32402549. IF: 4,957.

Troncoso-Mariño A, López-Jiménez T, Roso-Llorach A, Villén N, Amado-Guirado E, Guisado-Clavero M, Fernández-Bertolin S, Vigues MP, Foguet-Boreu Q, Violán C. Medication-related problems in older people in Catalonia: a real-world data study. Pharmacoepidemiol Drug Saf. 2020 Oct; doi:10.1002/pds.5149. Epub 2020 Oct 07. PMID:33026123. IF: 2,918.

Vetrano DL, Roso-Llorach A, Fernández S, Guisado-Clavero M, Violán C, Onder G, Fratiglioni L, Calderón-Larrañaga A, Marengoni A. Twelve-year clinical trajectories of multimorbidity in a population of older adults. Nat Commun. 2020 Jun; 11(1):3223. doi:10.1038/s41467-020-16780-x. Epub 2020 Jun 26. PMID:32591506. IF: 12,121.

Villén N, Guisado-Clavero M, Fernández-Bertolín S, Troncoso-Mariño A, Foguet-Boreu Q, Amado E, Pons-Vigués M, Roso-Llorach A, Violán C. Multimorbidity patterns, polypharmacy and their association with liver and kidney abnormalities in people over 65 years of age: a longitudinal study. BMC Geriatr. 2020 Jun; 20(1):206. doi:10.1186/s12877-020-01580-1. Epub 2020 Jun 12. pmc:PMC7291454. PMID:32532213. IF: 3,077.

Violán C, Fernández-Bertolín S, Guisado-Clavero M, Foguet-Boreu Q, Valderas JM, Vidal Manzano J, Roso-Llorach A, Cabrera-Bean M. Five-year trajectories of multimorbidity patterns in an elderly Mediterranean population using Hidden Markov Models. Sci Rep. 2020 Oct; 10(1):16879. doi:10.1038/s41598-020-73231-9. Epub 2020 Oct 09. PMID:33037233. IF: 3,998.

Master's Dissertation

López T [PhD student ]. Title: Síndrome metabólico y riesgo de cáncer: estudio caso-control con datos del Sistema de Información para el Desarrollo de la Investigación en Atención Primaria (SIDIAP) en Cataluña. 01/01/2020. Facultad de Medicina. Ongoing thesis.

Puente D, Plana O [Director]. Tomàs López [PhD student]. Síndrome metabólico y riesgo de cáncer: estudio caso-control con datos del Sistema de Información para el Desarrollo de la Investigación en Atención Primaria (SIDIAP) en Cataluña. 01/01/2020. Facultad de Medicina. Ongoing thesis.

Indicators

Indicator

2020

Researchers with PhD

11

Total number of projects in which group members have participated

71

Total number of projects in which the PI of the project has belonged to the group

47

Total Funding

3.444.435,27 €

Scientific publications in indexed journals

44

Total Impact factor

162,03

Nº of articles in Q1 journals

20

Q1 IF

111,24

Nº of articles in Q2 journals

14

Q2 IF

39,089

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