PI: Prieto Alhambra, Daniel. Non-interventional post-authorization multi-database safety study to further characterize specific safety outcomes in association with use of Entresto® (sacubitril/valsartan) in patients with heart failure. Safety. Funding: Pharmo Institute N.V. Duration: 2017 - 2022

PI: Duarte Salles, Talita. Body size and risk of development of 22 major cancers: Data from the Information System for the Development of Research in Primary Care collected on 6 million Catalans. Funding: WCRF NL Stichting Wereld Kanker Onderzoek Fonds. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. Desarrollo y validación de una Escala de Riesgo de Fracturas Implementable en historia clínica electrónica (EPIC). Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. High blood eosinophil levels as independent risk factor of severe asthma exacerbations and mortality in adult patients with asthma. Funding: Synapse Research Management Partners, S.L. Duration: 2018 - 2020

PI: Reyes Reyes, Carlen. Opioid drug utilisation and comparative safety: a population-based cohort study.. Funding: IDIAP Jordi Gol. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. The role of the microbiome in musculoskeletal disease. Funding: IDIAP Jordi Gol. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. Non-interventional post-authorization multi-database safety study to assess the risk of myotoxicity and hepatotoxicity in statin-exposed heart failure patients with or without concomitant use of LCZ696. Funding: Pharmo Institute N.V.. Duration: 2017 - 2020

PI: Prieto Alhambra, Daniel. Drug utilization study of mirabegron (Betmiga®) using real-world healthcare databases from the Netherlands, Spain, United Kingdom and Finland. Funding: Pharmo Institute N.V. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Multinational Observational Database Study on Imminent Osteoporotic Fracture Risk. Funding: University of Oxford. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Impacte del "audit and feedback" de la prevenció quaternària en pacients assignats a equips d'atenció primària a Catalunya del 2009 al 2016.. Funding: IDIAP Jordi Gol. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Advanced data analysis and management systems (Big Data solutions) in the identification and assessment of frailty risk profiles in populations, their evolution to disability, and their treatment. Funding: IDIAP Jordi Gol. Duration: 2017 - 2019

PI: Ramos Blanes, Rafel. Real world Outcomes across the AD spectrum to better care: Multi-modal data Access Platform. Funding: Innovative Medicines Initiative (IMI). Duration: 2018

PI: Martínez Laguna, Daniel. Eficacia de los fármacos para la osteoporosis en los pacientes con diabetes mellitus tipo 2: estudio de cohortes de base poblacional. Funding: FEIOMM. Duration: 2018

PI: Flores Mateo, Gemma. Efectivitat d'una xarxa de voluntaris activats de forma automàtica en la disminució del temps d'inici de les maniobres de Reanimació Cardiopulmonar. Funding: Fundació Academia Ciencies Mediques de Catalunya I de Balears (L'Acadèmia). Duration: 2017 - 2018

PI: Prieto Alhambra, Daniel. Secular trends of total knee/hip arthroplasty, related complications, and healthcare resource use in patients with inflammatory arthropathies compared to osteoarthritis: a binational cohort study.. Funding: IDIAP Jordi Gol. Duration: 2016 - 2018

PI: Bundo Vidiella, Magdalena. Incidència i evolució de les úlceres als peus dels pacients diabètics en atenció primària. Estudi multicèntric.. Funding: ICS - Institut Català de la Salut. Duration: 2016 - 2018

PI: Prieto Alhambra, Daniel. Multinational database cohort study to assess RMP specified safety outcomes in association with indacaterol/glycopyrronium bromide in Europe. QVA149A2402. Funding: Synapse Research Management Partners, S.L. Duration: 2014 - 2018

PI: Prieto Alhambra, Daniel. Multinational, multi-database cohort study to assess adverse cardiovascular and cerebrovascular outcomes and mortality in association with inhaled NVA237 in Europe. Funding: Synapse Research Management Partners, S.L. Duration: 2013 - 2018

Alarkawi D, Ali MS, Bliuc D, Center JR, Prieto-Alhambra D. The Challenges and Opportunities of Pharmacoepidemiology in Bone Diseases. JBMR plus. 2018 Jul; 2(4):187-194. doi:10.1002/jbm4.10051. Epub 2018 Apr 30. pmc:PMC6124176. PMID:30283902.

Alexander M, Loomis AK, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Avillach P, Egger P, Kendrick S, Waterworth DM, Sattar N, Alazawi W. Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease. BMC medicine. 2018 08; 16(1):130. doi:10.1186/s12916-018-1103-x. Epub 2018 Aug 13. pmc:PMC6088429. PMID:30099968. IF: 7,901.

Baena-Díez JM, Garcia-Gil M, Comas-Cufí M, Ramos R, Prieto-Alhambra D, Salvador-González B, Elosua R, Dégano IR, Peñafiel J, Grau M. Association between chronic immune-mediated inflammatory diseases and cardiovascular risk. Heart. 2018 Jan;104(2):119-126. doi: 10.1136/heartjnl-2017-311279. Epub 2017 Aug 28. PubMed PMID: 28847852. IF: 6,059.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Pinedo-Villanueva R, Prieto-Alhambra D. Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement: evidence from linked primary care and NHS hospital records from 1997 to 2014. BMJ open. 2018 01; 8(1):e019146. doi:10.1136/bmjopen-2017-019146. Epub 2018 Jan 27. pmc:PMC5829869. PMID:29374669. IF: 2,369.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Prieto-Alhambra D, Pinedo-Villanueva R. The impact of rheumatoid arthritis on the risk of adverse events following joint replacement: a real-world cohort study. Clinical epidemiology. 2018 ; 10:697-704. doi:10.2147/CLEP.S160347. Epub 2018 Jun 14. pmc:PMC6005318. PMID:29942159. IF: 7,056.

Cordtz RL, Hawley S, Prieto-Alhambra D, Højgaard P, Zobbe K, Overgaard S, Odgaard A, Kristensen LE, Dreyer L. Incidence of hip and knee replacement in patients with rheumatoid arthritis following the introduction of biological DMARDs: an interrupted time-series analysis using nationwide Danish healthcare registers. Annals of the rheumatic diseases. 2018 05; 77(5):684-689. doi:10.1136/annrheumdis-2017-212424. Epub 2017 Dec 15. PMID:29247125. IF: 12,811.

Ferguson RJ, Prieto-Alhambra D, Walker C, Yu D, Valderas JM, Judge A, Griffiths J, Jordan KP, Peat G, Glyn-Jones S, Silman AJ. Validation of hip osteoarthritis diagnosis recording in the UK Clinical Practice Research Datalink. Pharmacoepidemiology and drug safety. 2019 Feb; 28(2):187-193. doi:10.1002/pds.4673. Epub 2018 Oct 30. PMID:30375101. IF: 2,552.

Garriga C, Pazianas M, Hawley S, Delmestri A, Prieto-Alhambra D, Cooper C, Judge A. Oral bisphosphonate use and age-related macular degeneration: retrospective cohort and nested case-control study. Annals of the New York Academy of Sciences. 2018 Mar; 1415(1):34-46. doi:10.1111/nyas.13589. Epub 2018 Jan 24. pmc:PMC5886355. PMID:29363763. IF: 4,706.

Hawley S, Cordtz R, Dreyer L, Edwards CJ, Arden NK, Delmestri A, Silman A, Cooper C, Judge A, Prieto-Alhambra D. Association between NICE guidance on biologic therapies with rates of hip and knee replacement among rheumatoid arthritis patients in England and Wales: An interrupted time-series analysis. Seminars in arthritis and rheumatism. 2018 04; 47(5):605-610. doi:10.1016/j.semarthrit.2017.09.006. Epub 2017 Sep 23. pmc:PMC5866918. PMID:29055489. IF: 4,498.

Hawley S, Sacks S, Bowness P, Prieto-Alhambra D. Incidence of Total Hip and Knee Replacement in UK Patients with Ankylosing Spondylitis. The Journal of rheumatology. 2018 Aug; 45(9):1334-1336. doi:10.3899/jrheum.171387. PMID:30173183. IF: 3,150.

Khalid S, Calderon-Larrañaga S, Hawley S, Ali MS, Judge A, Arden N, van Staa T, Cooper C, Javaid MK, Prieto-Alhambra D. Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database. Clinical epidemiology. 2018 ; 10:1417-1431. doi:10.2147/CLEP.S164112. Epub 2018 Oct 09. pmc:PMC6183551. PMID:30349390. IF: 7,056.

Khan T, Alvand A, Prieto-Alhambra D, Culliford DJ, Judge A, Jackson WF, Scammell BE, Arden NK, Price AJ. ACL and meniscal injuries increase the risk of primary total knee replacement for osteoarthritis: a matched case-control study using the Clinical Practice Research Datalink (CPRD). British journal of sports medicine. 2018 Jan; doi:10.1136/bjsports-2017-097762. Epub 2018 Jan 13. PMID:29331994. IF: 6,557.

Kjørholt KE, Johnsen SP, Kristensen NR, Prieto-Alhambra D, Pedersen AB. Increasing Risk of Hospital-Treated Infections and Community-Based Antibiotic Use After Hip Fracture Surgery: A Nationwide Study 2005-2016. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2019 Mar; 34(3):437-446. doi:10.1002/jbmr.3620. Epub 2018 Dec 04. PMID:30515887. IF: 6,284.

Losada E, Soldevila B, Ali MS, Martínez-Laguna D, Nogués X, Puig-Domingo M, Díez-Pérez A, Mauricio D, Prieto-Alhambra D. Real-world antidiabetic drug use and fracture risk in 12,277 patients with type 2 diabetes mellitus: a nested case-control study. Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2018 Jun; doi:10.1007/s00198-018-4581-y. Epub 2018 Jun 02. PMID:29860664. IF: 3,591.

Lübbeke A, Silman AJ, Barea C, Prieto-Alhambra D, Carr AJ. Mapping existing hip and knee replacement registries in Europe. Health policy (Amsterdam, Netherlands). 2018 05; 122(5):548-557. doi:10.1016/j.healthpol.2018.03.010. Epub 2018 Mar 17. PMID:29598886. IF: 2,119.

Martínez-Laguna D, Tebé C, Nogués X, Kassim Javaid M, Cooper C, Moreno V, Diez-Perez A, Collins GS, Prieto-Alhambra D. Fracture risk in type 2 diabetic patients: A clinical prediction tool based on a large population-based cohort. PloS one. 2018 ; 13(9):e0203533. doi:10.1371/journal.pone.0203533. Epub 2018 Sep 07. pmc:PMC6128577. PMID:30192850. IF: 2,806.

Martín-Merino E, Calderón-Larrañaga A, Hawley S, Poblador-Plou B, Llorente-García A, Petersen I, Prieto-Alhambra D. The impact of different strategies to handle missing data on both precision and bias in a drug safety study: a multidatabase multinational population-based cohort study. Clinical epidemiology. 2018 ; 10:643-654. doi:10.2147/CLEP.S154914. Epub 2018 Jun 05. pmc:PMC5993167. PMID:29892204. IF: 7,056.

McCulloch L, Borthwick A, Redmond A, Edwards K, Pinedo-Villanueva R, Prieto-Alhambra D, Judge A, Arden NK, Bowen CJ. UK podiatrists' experiences of podiatry services for people living with arthritis: a qualitative investigation. Journal of foot and ankle research. 2018 ; 11:27. doi:10.1186/s13047-018-0262-5. Epub 2018 Jun 05. pmc:PMC5989380. PMID:29928316. IF: 1,405.

Morsley K, Miller A, Luqmani R, Fina-Aviles F, Javaid MK, Edwards CJ, Pinedo-Villanueva R, Medina M, Calero S, Cooper C, Arden N, Prieto-Alhambra D. Rheumatoid factor testing in Spanish primary care: A population-based cohort study including 4.8 million subjects and almost half a million measurements. Reumatologia clinica. 2018 Feb; doi:10.1016/j.reuma.2017.11.001. Epub 2018 Feb 26. PMID:29496419.

Olmos JM, Hernández JL, Martínez J, Pariente E, Castillo J, Prieto-Alhambra D, González-Macías J. Prevalence of vertebral fracture and densitometric osteoporosis in Spanish adult men: The Camargo Cohort Study. Journal of bone and mineral metabolism. 2018 Jan; 36(1):103-110. doi:10.1007/s00774-017-0812-0. Epub 2017 Jan 19. PMID:28102457. IF: 2,423.

Pérez-Sáez MJ, Herrera S, Prieto-Alhambra D, Vilaplana L, Nogués X, Vera M, Redondo-Pachón D, Mir M, Güerri R, Crespo M, Díez-Pérez A, Pascual J. Maintenance low dose systemic glucocorticoids have limited impact on bone strength and mineral density among incident renal allograft recipients: A pilot prospective cohort study. Bone. 2018 11; 116:290-294. doi:10.1016/j.bone.2018.08.013. Epub 2018 Aug 23. PMID:30145341. IF: 4,140.

Pontes C, Marsal JR, Elorza JM, Aragón M, Prieto-Alhambra D, Morros R. Analgesic Use and Risk for Acute Coronary Events in Patients With Osteoarthritis: A Population-based, Nested Case-control Study. Clin Ther. 2018 Feb;40(2):270-283. doi: 10.1016/j.clinthera.2017.12.011. Epub 2018 Feb 3. PubMed PMID: 29398161. IF: 2,947.

Prats-Uribe A, Tobías A, Prieto-Alhambra D. Excess Risk of Fatal Road Traffic Accidents on the Day of Daylight Saving Time Change. Epidemiology (Cambridge, Mass.). 2018 Sep; 29(5):e44-e45. doi:10.1097/EDE.0000000000000865. PMID:29864085. IF: 5,986.

Prieto-Alhambra D, Reyes C, Sainz MS, González-Macías J, Delgado LG, Bouzón CA, Gañan SM, Miedes DM, Vaquero-Cervino E, Bardaji MFB, Herrando LE, Baztán FB, Ferrer BL, Perez-Coto I, Bueno GA, Mora-Fernandez J, Doñate TE, Blasco JM, Aguado-Maestro I, Sáez-López P, Doménech MS, Climent-Peris V, Rodríguez ÁD, Sardiñas HK, Gómez ÓT, Serra JT, Caeiro-Rey JR, Cano IA, Carsi MB, Etxebarria-Foronda I, Hernández JDA, Solis JR, Suau OT, Nogués X, Herrera A, Díez-Perez A. In-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study. Archives of osteoporosis. 2018 Sep; 13(1):96. doi:10.1007/s11657-018-0515-8. Epub 2018 Sep 14. pmc:PMC6153683. PMID:30218380. IF: 1,960.

Reginster JL, Arden NK, Haugen IK, Rannou F, Cavalier E, Bruyère O, Branco J, Chapurlat R, Collaud Basset S, Al-Daghri NM, Dennison EM, Herrero-Beaumont G, Laslop A, Leeb BF, Maggi S, Mkinsi O, Povzun AS, Prieto-Alhambra D, Thomas T, Uebelhart D, Veronese N, Cooper C. Guidelines for the conduct of pharmacological clinical trials in hand osteoarthritis: Consensus of a Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Seminars in arthritis and rheumatism. 2018 08; 48(1):1-8. doi:10.1016/j.semarthrit.2017.12.003. Epub 2017 Dec 07. pmc:PMC5907911. PMID:29287769. IF: 4,498.

Roca-Ayats N, Ng PY, Garcia-Giralt N, Falcó-Mascaró M, Cozar M, Abril JF, Quesada Gómez JM, Prieto-Alhambra D, Nogués X, Dunford JE, Russell RG, Baron R, Grinberg D, Balcells S, Díez-Pérez A. Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2018 Dec; 33(12):2091-2098. doi:10.1002/jbmr.3580. Epub 2018 Sep 24. PMID:30184270. IF: 6,284.

Sáez-López P, González-Montalvo JI, Ojeda-Thies C, Mora-Fernández J, Muñoz-Pascual A, Cancio JM, Tarazona FJ, Pareja T, Gómez-Campelo P, Montero-Fernández N, Alarcón T, Mesa-Lampre P, Larrainzar-Gar R, Duaso E, Gil-Garay E, Diéz-Pérez A, Prieto-Alhambra D, Queipo-Matas R, Otero-Puime A; participants in the RNFC. Spanish National Hip Fracture Registry (SNHFR): a description of its objectives, methodology and implementation. Revista espanola de geriatria y gerontologia. 2018 Jul; 53(4):188-195. doi:10.1016/j.regg.2017.12.001. Epub 2018 Feb 14. PMID:29426794.

Tebé C, Martinez-Laguna D, Moreno V, Cooper C, Diez-Perez A, Collins GS, Prieto-Alhambra D. Differential Mortality and the Excess Rates of Hip Fracture Associated With Type 2 Diabetes: Accounting for Competing Risks in Fracture Prediction Matters. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2018 Aug; 33(8):1417-1421. doi:10.1002/jbmr.3435. Epub 2018 May 03. pmc:PMC6108421. PMID:29624726. IF: 6,284.

Researchers with PhD

15

Total number of projects in which group members have participated

19

Total number of projects in which the PI of the project has belonged to the group

15

Total Funding

827.424,19€

Scientific publications in indexed journals

25

Total Impact factor

122,5

Nº of articles in Q1 journals

17

Q1 IF

102,351

Nº of articles in Q2 journals

6

Q2 IF

16,319