ECONSAP

Research Group on Health Economics in Primary Care

Multidisciplinary group composed of six general practitioners (3 of them are also doctors in medicine), a nurse practitioner, three doctors in psychology, two doctors in pharmacy, two pharmacy graduates and a doctor in psychiatry. The group originated in 1999 under the name GRAPISAM Group (Research Group in Primary Care and Mental Health) with the development of the DAPGA study that was carried out in the Mental Health Center of Gavà and the ABS Bartolomé Fabrés Anglada of Gavà. As a result of that first collaboration, others emerged, such as the ETAPS, FIBROQOL and PRODEFAR studies, which focused mainly on the evaluation of interventions aimed at the management of mental illnesses in primary care, always with a focus on health economics. In recent years, the group has grown, becoming more multidisciplinary, expanding the focus of research and increasingly specializing in the economic evaluation of health in primary care, including the evaluation of the economic impact of diseases (eg COSTDEP), the cost-effectiveness of preventive interventions (eg PREDICTD-CCRT), the cost-effectiveness of pharmacological treatments (eg INFAP) and non-pharmacological treatments (eg EUDAIMON), the cost of non-adherence and the impact of the introduction of health policies (eg NO-Iniciadores), etc. In addition, although the study of mental illnesses is still one of the main focuses of the group, the research has been extended to other pathologies, such as the management of chronic pain and fibromyalgia (eg Fibromyalgia subtypes and EUDAIMON) or multi-risk prevention (eg Econ-EIRA3). The group complements the use of clinical trials and economic evaluations with other study designs that allow it to better understand the difficulties of managing pathologies in primary care and the efficiency of treatments, such as psychometric analysis (WHODAS 2.0, CERQ, FFMQ, MISCI, etc.), qualitative research (eg, PREDICT-EVAL), systematic reviews (eg EIRA2), and epidemiological studies based on the secondary exploitation of large databases, such as SIDIAP, all within the framework of research in the field of primary care. This evolution has given way to the Research Group on Health Economics in Primary Care (ECONSAP). The main objectives of the group are to improve the quality and efficiency of mental pathologies and chronic physical diseases care in Primary Care - including prevention and pharmacological and non-pharmacological treatment -, to assess the cost of diseases and patients? behavior and to develop innovative and multidisciplinary interventions in the area of Primary Care from a multidisciplinary point of view.

Group projects

PI: Bellon Saameño, Juan Angel. Prevención universal de la depresión y ansiedad en población general mediante una intervención personalizada basada en algoritmos de riesgo, TICs y sistemas de ayuda a las decisiones: ensayo controlado aleatorio. El estudio PredictPlusPrevent. Funding: Junta de Andalucia. Duration: 2019 - 2022

PI: Bellon Saameño, Juan Angel. Prevención de la depresión en el medio laboral mediante una intervención personalizada basada en algoritmos de riesgo, TICs y sistemas de ayuda a las decisiones: ensayo controlado aleatorio.. Funding: Instituto de Salud Carlos III. Duration: 2019 - 2021

PI: Mendive Arbeloa, Juan Manuel. Suport social i el seu impacte a la salut en el barri de La Mina: Seguiment i ampliació d'una cohort poblacional. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2020

PI: Rubio Valera, Maria. A non-interventional post-authorisation safety study (PASS) of vortioxetine in Europe An analysis of SIDIAP Database from Catalonia, Spain. Funding: H. Lundbeck A/S. Duration: 2018 - 2020

PI: Rubio Valera, Maria. Prevalencia e impacto de la no iniciación del tratamiento farmacológico en población pediátrica: estudio No Iniciadores-Pediátrico. Funding: Universidad Europea de Madrid S.L.U. Duration: 2019

PI: Rubio Valera, Maria. Modelado de la intervención compleja "Initial Medication Adherence" (IMA) en Atención Primaria: estudio No Iniciadores-Fase 1. Funding: Fund. privada per a la recerca i la Docència Sant Joan de Déu. Duration: 2018 - 2019

PI: Peñarrubia María, Mª Teresa. Impacto clínico y económico de la no iniciación de los tratamientos de prevención primaria de enfermedades cardiovasculares. Funding: Fundació d´Atenció Primària (CAMFiC) . Duration: 2018 - 2019

PI: Rubio Valera, Maria. Intervención del farmacéutico en el abordaje de la cesación tabáquica. Proyecto CESAR. Funding: Sociedad Española de Farmacia Familiar y Comunitarias (SEFAC). Duration: 2017 - 2019

The group participates in the following projects

PI: Luciano Devis, Juan Vicente. Efectos del peregrinaje en el Camino de Santiago sobre el bienestar psicológico y la salud mental. Funding: Fund. privada per a la recerca i la Docència Sant Joan de Déu. Duration: 2019 - 2021

PI: Luciano Devis, Juan Vicente. Cost-effectiveness of a Mindfulness-Based Stress Reduction (MBSR) treatment for fibromyalgia syndrome: A 12-month randomised, controlled trial. Funding: Instituto de Salud Carlos III. Duration: 2015 - 2020

PI: Luciano Devis, Juan Vicente. Efectos neurobiológicos de una intervención basada en mindfulness (MBSR) vs. Psico-educativa (FibroQol) en pacientes con fibromialgia (Proyecto EUDAIMON). Funding: Instituto de Salud Carlos III. Duration: 2016 - 2019

Group Publications

Andrés-Rodríguez L, Borràs X, Feliu-Soler A, Pérez-Aranda A, Angarita-Osorio N, Moreno-Peral P, Montero-Marin J, García-Campayo J, Carvalho AF, Maes M, Luciano JV. Peripheral immune aberrations in fibromyalgia: A systematic review, meta-analysis and meta-regression. Brain Behav. Immun. 2019 Dec; doi:10.1016/j.bbi.2019.12.020. Epub 2019 Dec 27. PMID:31887417. IF: 6,170.

Andrés-Rodríguez L, Borràs X, Feliu-Soler A, Pérez-Aranda A, Rozadilla-Sacanell A, Arranz B, Montero-Marin J, García-Campayo J, Angarita-Osorio N, Maes M, Luciano JV. Machine Learning to Understand the Immune-Inflammatory Pathways in Fibromyalgia. Int J Mol Sci. 2019 Aug; 20(17). doi:10.3390/ijms20174231. Epub 2019 Aug 29. pmc:PMC6747258. PMID:31470635. IF: 4,183.

Andrés-Rodríguez L, Borràs X, Feliu-Soler A, Pérez-Aranda A, Rozadilla-Sacanell A, Montero-Marin J, Maes M, Luciano JV. Immune-inflammatory pathways and clinical changes in fibromyalgia patients treated with Mindfulness-Based Stress Reduction (MBSR): A randomized, controlled clinical trial. Brain Behav. Immun. 2019 Feb; doi:10.1016/j.bbi.2019.02.030. Epub 2019 Feb 25. PMID:30818032. IF: 6,170.

Aznar I, Rubio M. Use of proton pump inhibitors among Danish children: A 16-year register-based nationwide study. Basic Clin Pharmacol Toxicol. 2019;124:704-710. PMID:30556952. IF: 2,452.

Aznar-Lou I, Carbonell-Duacastella C, Rodriguez A, Mera I, Rubio-Valera M. Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors. Nutrients. 2019 Oct; 11(10). doi:10.3390/nu11102466. Epub 2019 Oct 15. pmc:PMC6835757. PMID:31618867. IF: 4,171.

Aznar-Lou I, Iglesias-González M, Gil-Girbau M, Serrano-Blanco A, Fernández A, Peñarrubia-María MT, Sabés-Figuera R, Murrugarra-Centurión AG, March-Pujol M, Bolívar-Prados M, Rubio-Valera M. Corrigendum to "Impact of initial medication non-adherence to SSRIs on medical visits and sick leaves" [J Affect Disord. 2018 Jan 15;226:282-286]. J Affect Disord. 2019 Oct; 261:110. doi:10.1016/j.jad.2019.09.086. Epub 2019 Oct 11. PMID:31610310. IF: 4,084.

Aznar-Lou I, Iglesias-González M, Rubio-Valera M, Peñarrubia-Maria MT, Mendive JM, Murrugarra-Centurión AG, Gil-Girbau M, González-Suñer L, Peuters C, Serrano-Blanco A. Diagnostic accuracy and treatment approach to depression in primary care: predictive factors. Fam Pract. 2019 01; 36(1):3-11. doi:10.1093/fampra/cmy098. PMID:30423158. IF: 1,986.

Carbonell C, Aznar I, Peñarrubia M, Planchuelo D. Estat actual de la recerca sobre la no-iniciació a nivell mundial i a Catalunya. Circular farmacéutica. 2019;77(3):17-20.

Domènech-Abella J, Mundó J, Haro JM, Rubio-Valera M. Anxiety, depression, loneliness and social network in the elderly: Longitudinal associations from The Irish Longitudinal Study on Ageing (TILDA). J Affect Disord. 2019 Mar 1;246:82-88. doi: 10.1016/j.jad.2018.12.043. Epub 2018 Dec 17. Erratum in: J Affect Disord. 2020 Apr 1;266:811. PubMed PMID: 30578950. IF: 4,084.

Fayed N, Oliván B, Lopez Del Hoyo Y, Andrés E, Perez-Yus MC, Fayed A, Angel LF, Serrano-Blanco A, Roca M, Garcia Campayo J. Changes in metabolites in the brain of patients with fibromyalgia after treatment with an NMDA receptor antagonist. Neuroradiol J. 2019 Dec; 32(6):408-419. doi:10.1177/1971400919857544. Epub 2019 Jun 19. pmc:PMC6856999. PMID:31215319.

Feliu-Soler A, Pérez-Aranda A, Montero-Marín J, Herrera-Mercadal P, Andrés-Rodríguez L, Angarita-Osorio N, Williams AD, Luciano JV. Fifteen Years Controlling Unwanted Thoughts: A Systematic Review of the Thought Control Ability Questionnaire (TCAQ). Front Psychol. 2019 ; 10:1446. doi:10.3389/fpsyg.2019.01446. Epub 2019 Jun 19. pmc:PMC6593181. PMID:31275218. IF: 2,129.

Gil-Girbau M, Aznar-Lou I, Peñarrubia-María MT, Moreno-Peral P, Fernández A, Bellón JÁ, Jové AM, Mendive J, Fernández-Vergel R, Figueiras A, March-Pujol M, Rubio-Valera M. Reasons for medication non-initiation: A qualitative exploration of the patients' perspective. Res Social Adm Pharm. 2019 Aug; doi:10.1016/j.sapharm.2019.08.002. Epub 2019 Aug 06. PMID:31402307. IF: 2,719.

Gil-Girbau M, Pons-Vigués M, Rubio-Valera M, Murrugarra G, Masluk B, Rodríguez-Martín B, García Pineda A, Vidal Thomás C, Conejo-Cerón S, Recio JI, Martínez C, Pujol-Ribera E, Berenguera A. Theoretical models of health promotion in primary healthcare everyday practice. Gac Sanit. 2019 Nov; doi:10.1016/j.gaceta.2019.06.011. Epub 2019 Nov 18. Spanish. PMID:31753510. IF: 1,656.

Iracheta M. Automedida de la presión arterial (AMPA): herramienta de uso compartido entre diferentes profesionales sanitarios (caso clínico). Farmacéuticos comunitarios. 2019;11:1.

Iracheta M. Campaña de medida de la presión arterial (May Measurement Month) en 2017: análisis del cribado en farmacias comunitarias españolas. Farmacéuticos comunitarios. 2019;11(2):5-13.

Iracheta M. Determinación de pulso irregular en farmacias comunitarias españolas. Resultados del proyecto Know your pulse? 2016 y 2017?. Farmacéuticos comunitarios. 2019;11(4):5-20.

Iracheta M. MAPA en pacientes no frecuentadores del sistema sanitario. Una alternativa resolutiva de diagnóstico y control. Un caso clínico de diagnóstico y seguimiento. Farmacéuticos Comunitarios. Farmacéuticos comunitarios. 2019;11:1

Jiménez ML, Serrano A, Tiñena F, Escobar MÁ. Recomanacions de bones pràctiques en l'ús de mesures de restricció: avançant cap a la contenció mecànica zero. Annals de Medicina. 2019;102:165-169.

Luque V, Feliu A, Escribano J, Ferré N, Flores G, Monné R, Gutiérrez-Marín D, Guillen N, Muñoz-Hernando J, Zaragoza-Jordana M, Gispert-Llauradó M, Rubio-Torrents C, Núñez-Roig M, Alcázar M, Ferré R, Basora JM, Hsu P, Alegret-Basora C, Arasa F, Venables M, Singh P, Closa-Monasterolo R. The Obemat2.0 Study: A Clinical Trial of a Motivational Intervention for Childhood Obesity Treatment. Nutrients. 2019 Feb; 11(2). doi:10.3390/nu11020419. Epub 2019 Feb 16. pmc:PMC6413236. PMID:30781525. IF: 4,171.

Molinero A, Ruilope LM, Tous S, Fornos JA, Mera I, Andrés NF, Iracheta M, Xia X, Beaney T, Poulter NR, Rodilla E, Martínez F, Gijón-Conde T. May Measurement Month 2017: an analysis of blood pressure screening in Spain-Europe. Eur Heart J Suppl. 2019 Apr; 21(Suppl D):D107-D110. doi:10.1093/eurheartj/suz070. Epub 2019 Apr 24. pmc:PMC6479425. PMID:31043894. IF: 1,321.

Montero-Marin J, Andrés-Rodríguez L, Tops M, Luciano JV, Navarro-Gil M, Feliu-Soler A, López-Del-Hoyo Y, Garcia-Campayo J. Effects of attachment-based compassion therapy (ABCT) on brain-derived neurotrophic factor and low-grade inflammation among fibromyalgia patients: A randomized controlled trial. Sci Rep. 2019 Oct; 9(1):15639. doi:10.1038/s41598-019-52260-z. Epub 2019 Oct 30. pmc:PMC6821772. PMID:31666651. IF: 4,011.

Moreno-Peral P, Conejo-Cerón S, Fernández A, Martín-Pérez C, Fernández-Alonso C, Rodríguez-Bayón A, Ballesta-Rodríguez MI, Aiarzagüena JM, Montón-Franco C, King M, Nazareth I, Bellón JÁ. Family physicians' views on participating in prevention of major depression. The predictD-EVAL qualitative study. PLoS ONE. 2019 ; 14(5):e0217621. doi:10.1371/journal.pone.0217621. Epub 2019 May 30. PMID:31145762. IF: 2,776.

Parody E. Prevalencia y factores asociados a la adherencia terapéutica en pacientes de un programa integral de crónicos en un centro de atención primaria de Cali: comparación de diferentes test de adherencia. Pharm Care Esp. 2019;21(1):23-40.

Pérez-Aranda A, Andrés-Rodríguez L, Feliu-Soler A, Núñez C, Stephan-Otto C, Pastor-Mira MA, López-Roig S, Peñacoba C, Calandre EP, Slim M, Salgueiro M, Feixas G, Luciano JV. Clustering a large Spanish sample of patients with fibromyalgia using the Fibromyalgia Impact Questionnaire-Revised: differences in clinical outcomes, economic costs, inflammatory markers, and gray matter volumes. Pain. 2019 Apr;160(4):908-921. doi: 10.1097/j.pain.0000000000001468. PubMed PMID:30586023. IF: 6,029.

Pérez-Aranda A, Angarita-Osorio N, Feliu-Soler A, Andrés-Rodríguez L, Borràs X, Luciano JV. Do humor styles predict clinical response to the MINDSET (MINDfulneSs & EducaTion) program? A pilot study in patients with fibromyalgia. Reumatol Clin. 2019 Dec; doi:10.1016/j.reuma.2019.10.002. Epub 2019 Dec 07. PMID:31822445.

Pérez-Aranda A, D'Amico F, Feliu-Soler A, McCracken LM, Peñarrubia-María MT, Andrés-Rodríguez L, Angarita-Osorio N, Knapp M, García-Campayo J, Luciano JV. Cost-Utility of Mindfulness-Based Stress Reduction for Fibromyalgia versus a Multicomponent Intervention and Usual Care: A 12-Month Randomized Controlled Trial (EUDAIMON Study). J Clin Med. 2019 Jul; 8(7). doi:10.3390/jcm8071068. Epub 2019 Jul 20. pmc:PMC6678679. PMID:31330832. IF: 5,688.

Pérez-Aranda A, Feliu-Soler A, Montero-Marín J, García-Campayo J, Andrés-Rodríguez L, Borràs X, Rozadilla-Sacanell A, Peñarrubia-Maria MT, Angarita-Osorio N, McCracken LM, Luciano JV. A randomized controlled efficacy trial of mindfulness-based stress reduction compared with an active control group and usual care for fibromyalgia: the EUDAIMON study. Pain. 2019 Nov; 160(11):2508-2523. doi:10.1097/j.Pain.0000000000001655. PMID:31356450. IF: 6,029.

Pérez-Aranda A, Hofmann J, Feliu-Soler A, Ramírez-Maestre C, Andrés-Rodríguez L, Ruch W, Luciano JV. Laughing away the pain: A narrative review of humour, sense of humour and pain. Eur J Pain. 2019 Feb;23(2):220-233. doi: 10.1002/ejp.1309. Epub 2018 Sep 30. Review. PubMed PMID: 30176100. IF: 3,188.

Rubio-Valera M, Peñarrubia-María MT, Iglesias-González M, Knapp M, McCrone P, Roig M, Sabes-Figuera R, Luciano JV, Mendive JM, Murrugara-Centurión AG, Alonso J, Serrano-Blanco A. Cost-effectiveness of antidepressants versus active monitoring for mild-to-moderate major depressive disorder: a multisite non-randomized-controlled trial in primary care (INFAP study). Eur J Health Econ. 2019 Feb; doi:10.1007/s10198-019-01034-5. Epub 2019 Feb 06. PMID:30725226. IF: 2,169.

Vilar A, Pérez-Sola V, Blasco MJ, Pérez-Gallo E, Ballester Coma L, Batlle Vila S, Alonso J, Serrano-Blanco A, Forero CG. Translational research in psychiatry: The Research Domain Criteria Project (RDoC). Rev Psiquiatr Salud Ment. 2019 Jul - Sep;12(3):187-195. doi: 10.1016/j.rpsm.2018.04.002. Epub 2018 Jun 23. English, Spanish. PubMed PMID: 29941228. IF: 2,927.

Indicators

Indicator

2019

Researchers with PhD

10

Total number of projects in which group members have participated

11

Total number of projects in which the PI of the project has belonged to the group

9

Total Funding

663.094,06€

Scientific publications in indexed journals

21

Total Impact factor

78,11

Nº of articles in Q1 journals

12

Q1 IF

55,495

Nº of articles in Q2 journals

7

Q2 IF

18,845

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