PI: Prieto Alhambra, Daniel. Non-interventional post-authorization multi-database safety study to further characterize specific safety outcomes in association with use of Entresto® (sacubitril/valsartan) in patients with heart failure. Safety. Funding: Pharmo Institute N.V. Duration: 2017 - 2022

PI: Canivell Fusté, Silvia. Caracterización del riesgo fracturario en pacientes diabéticos mayores de 50 años tratados con SGLT2 inhibidores. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Prieto Alhambra, Daniel. Comorbidities in osteoarthritis. Funding: Foundation for Research in Rheumatology (foreum). Duration: 2019 - 2021

PI: Reyes Reyes, Carlen. Estimating Short-Term and Long-Term Direct Economic Burden Associated with Osteoporotic Fracture. Funding: IQVIA World Publications Ltd.. Duration: 2019 - 2021

PI: Prieto Alhambra, Daniel. A retrospective cohort study to assess modification of VKA and DOAC treatment effectiveness and safety among patients with atrial fibrillation in three countries. Funding: University of Oxford. Duration: 2019 - 2021

PI: Prieto Alhambra, Daniel. A retrospective cohort study to assess drug utilisation and long-term safety of galcanezumab in European patients in the course of routine clinical care. Funding: University of Oxford. Duration: 2019 - 2021

PI: Alfonso Boguña, Marta. Salut al dia: Efectivitat d'un programa de promoció de la salut en l'adolescència en l'àmbit escolar. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Duarte Salles, Talita. Body size and risk of development of 22 major cancers: Data from the Information System for the Development of Research in Primary Care collected on 6 million Catalans. Funding: WCRF NL Stichting Wereld Kanker Onderzoek Fonds. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. Desarrollo y validación de una Escala de Riesgo de Fracturas Implementable en historia clínica electrónica (EPIC). Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. High blood eosinophil levels as independent risk factor of severe asthma exacerbations and mortality in adult patients with asthma. Funding: Synapse Research Management Partners, S.L. Duration: 2018 - 2020

PI: Reyes Reyes, Carlen. Opioid drug utilisation and comparative safety: a population-based cohort study.. Funding: IDIAP Jordi Gol. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. The role of the microbiome in musculoskeletal disease. Funding: IDIAP Jordi Gol. Duration: 2018 - 2020

PI: Prieto Alhambra, Daniel. Non-interventional post-authorization multi-database safety study to assess the risk of myotoxicity and hepatotoxicity in statin-exposed heart failure patients with or without concomitant use of LCZ696. Funding: Pharmo Institute N.V.. Duration: 2017 - 2020

PI: Prieto Alhambra, Daniel. European Non-interventional Post Authorization Safety Study for romosozumab by the EU-ADR Alliance. Funding: Synapse Research Management Partners, S.L. Duration: 2019

PI: Prieto Alhambra, Daniel. Drug utilization study of mirabegron (Betmiga®) using real-world healthcare databases from the Netherlands, Spain, United Kingdom and Finland. Funding: Pharmo Institute N.V.. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Multinational Observational Database Study on Imminent Osteoporotic Fracture Risk. Funding: University of Oxford. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Impacte del "audit and feedback" de la prevenció quaternària en pacients assignats a equips d'atenció primària a Catalunya del 2009 al 2016. Funding: IDIAP Jordi Gol. Duration: 2017 - 2019

PI: Prieto Alhambra, Daniel. Advanced data analysis and management systems (Big Data solutions) in the identification and assessment of frailty risk profiles in populations, their evolution to disability, and their treatment. Funding: IDIAP Jordi Gol. Duration: 2017 - 2019

Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Avillach P, Egger P, Dhalwani NN, Kendrick S, Celis-Morales C, Waterworth DM, Alazawi W, Sattar N. Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. BMJ. 2019 10; 367:l5367. doi:10.1136/bmj.l5367. Epub 2019 Oct 08. pmc:PMC6780322. PMID:31594780. IF: 27,604.

Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Waterworth DM, Kendrick S, Sattar N, Alazawi W. Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts. BMC Med. 2019 May; 17(1):95. doi:10.1186/s12916-019-1321-x. Epub 2019 May 20. PMID:31104631. IF: 8,285.

Ali MS, Prieto-Alhambra D, Lopes LC, Ramos D, Bispo N, Ichihara MY, Pescarini JM, Williamson E, Fiaccone RL, Barreto ML, Smeeth L. Propensity Score Methods in Health Technology Assessment: Principles, Extended Applications, and Recent Advances. Front Pharmacol. 2019 ; 10:973. doi:10.3389/fphar.2019.00973. Epub 2019 Sep 18. pmc:PMC6760465. PMID:31619986. IF: 3,845.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Pinedo-Villanueva R, Prieto-Alhambra D. Lifetime risk of knee and hip replacement following a diagnosis of RA: findings from a cohort of 13 961 patients from England. Rheumatology (Oxford). 2019 Nov; 58(11):1950-1954. doi:10.1093/rheumatology/kez143. pmc:PMC6848958. PMID:31127844. IF: 5,149.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Pinedo-Villanueva R, Prieto-Alhambra D. Lifetime risk of knee and hip replacement following a diagnosis of RA: findings from a cohort of 13 961 patients from England. Rheumatology (Oxford). 2019 Nov; 58(11):2078. doi:10.1093/rheumatology/kez223. PMID:31121033. IF: 5,149.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Pinedo-Villanueva R, Prieto-Alhambra D. The effect of rheumatoid arthritis on patient-reported outcomes following knee and hip replacement: evidence from routinely collected data. Rheumatology (Oxford). 2019 Jan; doi:10.1093/rheumatology/key409. Epub 2019 Jan 03. PMID:30608608. IF: 5,149.

Burn E, Edwards CJ, Murray DW, Silman A, Cooper C, Arden NK, Prieto-Alhambra D, Pinedo-Villanueva R. The impact of BMI and smoking on risk of revision following knee and hip replacement surgery: evidence from routinely collected data. Osteoarthr. Cartil. 2019 Sep; 27(9):1294-1300. doi:10.1016/j.joca.2019.05.012. Epub 2019 May 30. PMID:31153986. IF: 4,879.

Burn E, Murray DW, Hawker GA, Pinedo-Villanueva R, Prieto-Alhambra D. Lifetime risk of knee and hip replacement following a GP diagnosis of osteoarthritis: a real-world cohort study. Osteoarthr. Cartil. 2019 Nov; 27(11):1627-1635. doi:10.1016/j.joca.2019.06.004. Epub 2019 Jun 17. PMID:31220608. IF: 4,879.

Burn E, Murray DW, Pinedo-Villanueva R, Prieto-Alhambra D. Knee and hip replacements and the risk of revision. Lancet. 2019 08; 394(10200):e28. doi:10.1016/S0140-6736(19)31780-5. PMID:31478504. IF: 59,102.

Cehic M, Lerner RG, Achten J, Griffin XL, Prieto-Alhambra D, Costa ML. Prescribing and adherence to bone protection medications following hip fracture in the United Kingdom: results from the World Hip Trauma Evaluation (WHiTE) cohort study. Bone Joint J. 2019 11; 101-B(11):1402-1407. doi:10.1302/0301-620X.101B11.BJJ-2019-0387.R1. PMID:31674239. IF: 4,301.

Dennison EM, Cooper C, Kanis JA, Bruyère O, Silverman S, McCloskey E, Abrahamsen B, Prieto-Alhambra D, Ferrari S; IOF Epidemiology/Quality of Life Working Group. Fracture risk following intermission of osteoporosis therapy. Osteoporos Int. 2019 Sep; 30(9):1733-1743. doi:10.1007/s00198-019-05002-w. Epub 2019 Jun 07. PMID:31175404. IF: 3,819.

Ferguson R, Culliford D, Prieto-Alhambra D, Pinedo-Villanueva R, Delmestri A, Arden N, Bowen C. Encounters for foot and ankle pain in UK primary care: a population-based cohort study of CPRD data. Br J Gen Pract. 2019 Jun; 69(683):e422-e429. doi:10.3399/bjgp19X703817. Epub 2019 May 20. pmc:PMC6532799. PMID:31109927. IF: 4,434.

Garcia-Gil M, Comas-Cufí M, Ramos R, Martí R, Alves-Cabratosa L, Parramon D, Prieto-Alhambra D, Baena-Díez JM, Salvador-González B, Elosua R, Dégano IR, Marrugat J, Grau M. Effectiveness of Statins as Primary Prevention in People With Gout: A Population-Based Cohort Study. J. Cardiovasc. Pharmacol. Ther. 2019 Nov; 24(6):542-550. doi:10.1177/1074248419857071. Epub 2019 Jun 27. PMID:31248268. IF: 2,570.

Garriga C, Murphy J, Leal J, Arden NK, Price AJ, Prieto-Alhambra D, Carr AJ, Rangan A, Cooper C, Peat G, Fitzpatrick R, Barker KL, Judge A. Assessment on patient outcomes of primary hip replacement: an interrupted time series analysis from 'The National Joint Registry of England and Wales'. BMJ Open. 2019 Nov; 9(11):e031599. doi:10.1136/bmjopen-2019-031599. Epub 2019 Nov 21. pmc:PMC6887059. PMID:31753882. IF: 2,376.

Garriga C, Murphy J, Leal J, Price A, Prieto-Alhambra D, Carr A, Arden NK, Rangan A, Cooper C, Peat G, Fitzpatrick R, Barker K, Judge A. Impact of a national enhanced recovery after surgery programme on patient outcomes of primary total knee replacement: an interrupted time series analysis from "The National Joint Registry of England, Wales, Northern Ireland and the Isle of Man". Osteoarthr. Cartil. 2019 Sep; 27(9):1280-1293. doi:10.1016/j.joca.2019.05.001. Epub 2019 May 10. PMID:31078777. IF: 4,879.

Hawley S, Ali MS, Cordtz R, Dreyer L, Edwards CJ, Arden NK, Cooper C, Judge A, Hyrich K, Prieto-Alhambra D. Impact of TNF inhibitor therapy on joint replacement rates in rheumatoid arthritis: a matched cohort analysis of BSRBR-RA UK registry data. Rheumatology (Oxford). 2019 Jan; doi:10.1093/rheumatology/key424. Epub 2019 Jan 10. PMID:30649521. IF: 5,149.

Khan T, Alvand A, Prieto-Alhambra D, Culliford DJ, Judge A, Jackson WF, Scammell BE, Arden NK, Price AJ. ACL and meniscal injuries increase the risk of primary total knee replacement for osteoarthritis: a matched case-control study using the Clinical Practice Research Datalink (CPRD). Br J Sports Med. 2018 Jan; doi:10.1136/bjsports-2017-097762. Epub 2018 Jan 13. PMID:29331994. IF: 11,645.

Kjørholt KE, Kristensen NR, Prieto-Alhambra D, Johnsen SP, Pedersen AB. Increased risk of mortality after postoperative infection in hip fracture patients. Bone. 2019 Oct; 127:563-570. doi:10.1016/j.Bone.2019.07.023. Epub 2019 Jul 21. PMID:31340186. IF: 4,360.

Kolovos S, Nador G, Kishore B, Streetly M, Rabin NK, Chantry AD, Yong K, Ashcroft J, Bowcock S, Drayson MT, Ramasamy K, Prieto-Alhambra D, Cooper C, Javaid MK, Pinedo-Villanueva R. Unplanned admissions for patients with myeloma in the UK: Low frequency but high costs. J Bone Oncol. 2019 Aug; 17:100243. doi:10.1016/j.jbo.2019.100243. Epub 2019 Jun 07. pmc:PMC6579752. PMID:31223562. IF: 2,866.

Martinez-Laguna D, Soria-Castro A, Carbonell-Abella C, Orozco-López P, Estrada-Laza P, Nogues X, Díez-Perez A, Prieto-Alhambra D. Validation of fragility fractures in primary care electronic medical records: A population-based study. Reumatol Clin. 2019 Sep; 15(5):e1-e4. doi:10.1016/j.reuma.2017.10.013. Epub 2017 Nov 28. PMID:29195740.

Morsley K, Miller A, Luqmani R, Fina-Aviles F, Javaid MK, Edwards CJ, Pinedo-Villanueva R, Medina M, Calero S, Cooper C, Arden N, Prieto-Alhambra D. Rheumatoid factor testing in Spanish primary care: A population-based cohort study including 4.8 million subjects and almost half a million measurements. Reumatol Clin. 2019 Nov - Dec;15(6):350-354. doi: 10.1016/j.reuma.2017.11.001. Epub 2018 Feb 26. English, Spanish. PubMed PMID: 29496419.

Nagra NS, Robinson DE, Douglas I, Delmestri A, Dakin SG, Snelling SJB, Carr AJ, Prieto-Alhambra D. Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD. Sci Rep. 2019 Jun; 9(1):8941. doi:10.1038/s41598-019-45435-1. Epub 2019 Jun 20. pmc:PMC6586671. PMID:31222078. IF: 4,011.

Pedersen AB, Heide-Jørgensen U, Sørensen HT, Prieto-Alhambra D, Ehrenstein V. Comparison of Risk of Osteoporotic Fracture in Denosumab vs Alendronate Treatment Within 3 Years of Initiation. JAMA Netw Open. 2019 Apr; 2(4):e192416. doi:10.1001/jamanetworkopen.2019.2416. Epub 2019 Apr 05. PMID:31002319.

Tebé C, Martínez-Laguna D, Carbonell-Abella C, Reyes C, Moreno V, Diez-Perez A, Collins GS, Prieto-Alhambra D. The association between type 2 diabetes mellitus, hip fracture, and post-hip fracture mortality: a multi-state cohort analysis. Osteoporos Int. 2019 Dec; 30(12):2407-2415. doi:10.1007/s00198-019-05122-3. Epub 2019 Aug 23. PMID:31444526. IF: 3,819.

Thorlund JB, Turkiewicz A, Prieto-Alhambra D, Englund M. Opioid use in knee or hip osteoarthritis: a region-wide population-based cohort study. Osteoarthr. Cartil. 2019 Jan; doi:10.1016/j.joca.2019.01.005. Epub 2019 Jan 22. PMID:30682417. IF: 4,879.

Wright JG, Davies J, Barwick MA, Hawker GA, Prieto-Alhambra D, Coyte PC. What Systematic Reviews Exist for the Effectiveness of Orthopaedic Interventions. J Am Acad Orthop Surg Glob Res Rev. 2019 Feb; 3(2):e098. doi:10.5435/JAAOSGlobal-D-18-00098. Epub 2019 Feb 05. pmc:PMC6587513. PMID:31334473.

Researchers with PhD

9

Total number of projects in which group members have participated

18

Total number of projects in which the PI of the project has belonged to the group

15

Total Funding

1.079.722,19€

Scientific publications in indexed journals

22

Total Impact factor

183,15

Nº of articles in Q1 journals

17

Q1 IF

167,699

Nº of articles in Q2 journals

4

Q2 IF

12,584