ISV-Girona

Girona Vascular Health Research Group

The ISV group is fully integrated in the cardiovascular area of the IDIAP since the main researcher of the group is, in turn, the area coordinator. He has participated with great involvement in the cardiovascular group of the AIAPP network through the leadership of the CARDIOCAT group (the seven members of the ISV group belong to CARDIOCAT and its IP also belongs to the CARDIOCAT). On the other hand, it is also present through its PI (which performs the tasks of coordinator) in the vascular prevention group of the Vascular Diseases Plan of the Department of Health of the Generalitat de Catalunya. The members of the ISV belong to different areas of the Primary Health care system, including management, teaching, patient care and research. The central research objective of the group is to improve the detection and management of patients with intermediate cardiovascular risk, the detection of CV disease in the asymptomatic phase and to analyze the cost effectiveness of interventions for the prevention of cardiovascular disease.

Group projects

PI: Ponjoan Thans, Anna. Smart City Observatories implement REsilient Water Management. Funding: Fundació Institut Català de Recerca de l'Aigua (ICRA). Duration: 2019 - 2021

PI: Romero Garcia, Ana. Intervención sobre conocimientos de prevención de úlceras por presión y alimentación en cuidadores formales de personas con Atención Domiciliaria en ABS Girona. Funding: ICS - Institut Català de la Salut. Duration: 2019 - 2021

PI: Ramos Blanes, Rafel. Predicción del Riesgo vascular en pOblación de edad avanzada del mediTErraneO. Estudio PROTEO. Funding: Instituto de Salud Carlos III. Duration: 2018 - 2020

PI: Martí Lluch, Ruth. Trastorns afectius i risc cardiovascular en població general: efecte diferencial dels mecanismes fisiopatològics. Funding: Departament de Salut. Duration: 2018 - 2020

PI: Garcia Gil, Mª del Mar. Retrospective longitudinal analysis in T1D and T2D for the population of Catalonia. Funding: Novo Nordisk Pharma, S.A. Duration: 2018 - 2019

PI: Garcia Gil, Mª del Mar. Efectividad de los Objetivos Terapéuticos de la Lipoproteina de Baja Densidad (cLDL) en la Reducción de Eventos Aterotrombóticos. Proyecto ELECTRA. Funding: Instituto de Salud Carlos III. Duration: 2017 - 2019

PI: Rodriguez Poncelas, Antonio. Asociación entre la administración de inhibidores de la bomba de protocones y la incidencia de enfermedad renal crónica y lesion renal aguda en población general. Funding: IDIAP Jordi Gol. Duration: 2017 - 2019

PI: Elosua Llanos, Roberto. Seguiment de la cohort poblacional de l'estudi REGICOR: tendències en la incidència de malaltia cardiovascular, en la prevalença de factors de risc, identificació de nous mecanismes i biomarcadors predictius, i avaluació d'estratègies de prevenció.. Funding: Fundació IMIM (Fundació Institut Mar d'Investigacions Mèdiques). Duration: 2017 - 2019

PI: Ramos Blanes, Rafel. Epidemiologia de la Hipercolesterolèmia Familiar; predicció de risc, efectivitat i seguretat del tractament hipolipemiant. Funding: Departament de Salut. Duration: 2017 - 2019

PI: Cerezo Goyeneche, Carlos. Ensayo híbrido de evaluación de una intervención compleja multiriesgo para promover conductas saludables en personas de 45-75 años atendidas en Atención Primaria: estudio EIRA3. Subproyecto Girona. Funding: Instituto de Salud Carlos III. Duration: 2016 - 2019

Group publications

Alves-Cabratosa L, Elosua-Bayes M, García-Gil M, Comas-Cufí M, Martí-Lluch R, Ponjoan A, Blanch J, Parramon D, Gomez-Marcos MA, Ramos R. Hypertension and high ankle brachial index: the overlooked combination. J. Hypertens. 2019 Jan; 37(1):92-98. doi:10.1097/HJH.0000000000001861. PMID:30507863. IF: 4,209.

Alves-Cabratosa L, Garcia-Gil M, Comas-Cufí M, Blanch J, Ponjoan A, Martí-Lluch R, Elosua-Bayes M, Parramon D, Camós L, Ramos R. Role of Low Ankle-Brachial Index in Cardiovascular and Mortality Risk Compared with Major Risk Conditions. J Clin Med. 2019 Jun; 8(6). doi:10.3390/jcm8060870. Epub 2019 Jun 18. pmc:PMC6617200. PMID:31216703. IF: 5,688.

Bonmatí-Tomas A, Malagón-Aguilera MC, Gelabert-Vilella S, Bosch-Farré C, Vaandrager L, García-Gil MM, Juvinyà-Canal D. Salutogenic health promotion program for migrant women at risk of social exclusion. Int J Equity Health. 2019 Sep; 18(1):139. doi:10.1186/s12939-019-1032-0. Epub 2019 Sep 03. PMID:31481094. IF: 2,473.

Coll-de-Tuero G, Comas-Cufí M, Rodríguez-Poncelas A, Barrot-de-la Puente J, Blanch J, Figa-Vaello J, Barceló MA, Saez M. Prognostic value of the estimated glomerular filtration rate decline in hypertensive patients without chronic kidney disease. Am. J. Hypertens. 2019 Feb; doi:10.1093/ajh/hpz029. Epub 2019 Feb 22. PMID:30794282. IF: 2,530.

Dégano IR, Ramos R, García-Gil M, Zamora A, Comas-Cufí M, Francés A, Garcia-Elias A, Marrugat J. Three-year events and mortality in cardiovascular disease patients without lipid-lowering treatment. Eur J Prev Cardiol. 2019 Jul; doi:10.1177/2047487319862103. Epub 2019 Jul 09. PMID:31288537. IF: 5,640.

Fa-Binefa M, Clará A, Pérez-Fernández S, Grau M, Dégano IR, Marti-Lluch R, Ramos R, Marrugat J, Elosua R. Early smoking-onset age and risk of cardiovascular disease and mortality. Prev Med. 2019 07; 124:17-22. doi:10.1016/j.ypmed.2019.04.022. Epub 2019 May 02. PMID:31054906. IF: 3,449.

Garcia-Gil M, Comas-Cufí M, Ramos R, Martí R, Alves-Cabratosa L, Parramon D, Prieto-Alhambra D, Baena-Díez JM, Salvador-González B, Elosua R, Dégano IR, Marrugat J, Grau M. Effectiveness of Statins as Primary Prevention in People With Gout: A Population-Based Cohort Study. J. Cardiovasc. Pharmacol. Ther. 2019 Nov; 24(6):542-550. doi:10.1177/1074248419857071. Epub 2019 Jun 27. PMID:31248268. IF: 2,570.

Garre-Olmo J, Ponjoan A, Inoriza JM, Blanch J, Sánchez-Pérez I, Cubí R, de Eugenio R, Turró-Garriga O, Vilalta-Franch J. Survival, effect measures, and impact numbers after dementia diagnosis: a matched cohort study. Clin Epidemiol. 2019 ; 11:525-542. doi:10.2147/CLEP.S213228. Epub 2019 Jul 16. pmc:PMC6645613. PMID:31410066. IF: 3,178.

Gomez-Marcos MA, Gomez-Sanchez L, Patino-Alonso MC, Recio-Rodriguez JI, Gomez-Sanchez M, Rigo F, Marti R, Agudo-Conde C, Maderuelo-Fernandez JA, Ramos R, Garcia-Ortiz L, Rodriguez-Sanchez E. Capacity adiposity indices to identify metabolic syndrome in subjects with intermediate cardiovascular risk (MARK study). PLoS ONE. 2019 ; 14(1):e0209992. doi:10.1371/journal.pone.0209992. Epub 2019 Jan 25. pmc:PMC6347134. PMID:30682054. IF: 2,776.

Gomez-Sanchez L, Gomez-Marcos MA, Patino-Alonso MC, Recio-Rodriguez JI, Gomez-Sanchez M, González-Sánchez J, Alonso-Domínguez R, Sánchez-Aguadero N, Maderuelo-Fernandez JA, Ramos R, Garcia-Ortiz L, Rodriguez-Sanchez E; MARK Group. Reclassification by applying the Framingham equation 30 years to subjects with intermediate cardiovascular risk. MARK study. Med Clin (Barc). 2019 Mar; doi:10.1016/j.medcli.2019.01.033. Epub 2019 Mar 28. PMID:30929863. IF: 1,277.

Janssen O, Vos SJB, García-Negredo G, Tochel C, Gustavsson A, Smith M, Ly A, Nelson M, Baldwin H, Sudlow C, Bexelius C, Jindra C, Vaci N, Bauermeister S, Gallacher J, Ponjoan A, Dufouil C, Garre Olmo J, Pedersen L, Skoog I, Hottgenroth A, Visser PJ, van der Lei J, Diaz C. Real-world evidence in Alzheimer's disease: The ROADMAP Data Cube. Alzheimers Dement. 2019 Nov; doi:10.1016/j.jalz.2019.09.087. Epub 2019 Nov 27. PMID:31786128. IF: 14,423.

Masana L, Zamora A, Plana N, Comas-Cufí M, Garcia-Gil M, Martí-Lluch R, Ponjoan A, Alves-Cabratosa L, Elosua R, Marrugat J, Dégano IR, Ramos R. Incidence of Cardiovascular Disease in Patients with Familial Hypercholesterolemia Phenotype: Analysis of 5 Years Follow-Up of Real-World Data from More than 1.5 Million Patients. J Clin Med. 2019 Jul; 8(7). doi:10.3390/jcm8071080. Epub 2019 Jul 23. pmc:PMC6678686. PMID:31340450. IF: 5,688.

NCD Risk Factor Collaboration (NCD-RisC). Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Nature. 2019 May;569(7755):260-264. doi: 10.1038/s41586-019-1171-x. Epub 2019 May 8. PubMed PMID: 31068725; PubMed Central PMCID: PMC6784868. IF: 43,070.

NCD Risk Factor Collaboration . National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries. Int J Epidemiol. 2019 Jul 18. pii: dyz099. doi: 10.1093/ije/dyz099. [Epub ahead of print] PubMed PMID: 31321439. IF: 7,339.

Ponjoan A, Garre-Olmo J, Blanch J, Fages E, Alves-Cabratosa L, Martí-Lluch R, Comas-Cufí M, Parramon D, Garcia-Gil M, Ramos R. Epidemiology of dementia: prevalence and incidence estimates using validated electronic health records from primary care. Clin Epidemiol. 2019 ; 11:217-228. doi:10.2147/CLEP.S186590. Epub 2019 Mar 04. pmc:PMC6407519. PMID:30881138. IF: 3,178.

Ponjoan A, Garre-Olmo J, Blanch J, Fages E, Alves-Cabratosa L, Martí-Lluch R, Comas-Cufí M, Parramon D, García-Gil M, Ramos R. How well can electronic health records from primary care identify Alzheimer's disease cases?. Clin Epidemiol. 2019 ; 11:509-518. doi:10.2147/CLEP.S206770. Epub 2019 Jul 05. pmc:PMC6620769. PMID:31456649. IF: 3,178.

Ramos R, Masana L, Comas-Cufí M, García-Gil M, Martí-Lluch R, Ponjoan A, Plana N, Alves-Cabratosa L, Marrugat J, Elosua R, Dégano IR, Gomez-Marcos MA, Zamora A. Derivation and validation of SIDIAP-FHP score: A new risk model predicting cardiovascular disease in familial hypercholesterolemia phenotype. Atherosclerosis. 2019 Oct; 292:42-51. doi:10.1016/j.Atherosclerosis.2019.10.016. Epub 2019 Oct 30. PMID:31759248. IF: 4,255.

Recalde M, Manzano-Salgado CB, Díaz Y, Puente D, Garcia-Gil MDM, Marcos-Gragera R, Ribes-Puig J, Galceran J, Posso M, Macià F, Duarte-Salles T. Validation Of Cancer Diagnoses In Electronic Health Records: Results From The Information System For Research In Primary Care (SIDIAP) In Northeast Spain. Clin Epidemiol. 2019 ; 11:1015-1024. doi:10.2147/CLEP.S225568. Epub 2019 Dec 03. pmc:PMC6899079. PMID:31819655. IF: 3,178.

Tochel C, Smith M, Baldwin H, Gustavsson A, Ly A, Bexelius C, Nelson M, Bintener C, Fantoni E, Garre-Olmo J, Janssen O, Jindra C, Jørgensen IF, McKeown A, Öztürk B, Ponjoan A, Potashman MH, Reed C, Roncancio-Diaz E, Vos S, Sudlow C; ROADMAP consortium. What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals? A?systematic review. Alzheimers Dement (Amst). 2019 Dec; 11:231-247. doi:10.1016/j.dadm.2018.12.003. Epub 2019 Mar 07. pmc:PMC6411507. PMID:30906845.

Zamora A, Masana L, Plana N, Ramos R. Estimated Percentage of Patients With Stable Coronary Heart Disease Candidates for PCSK9 Inhibitors. Response. Rev Esp Cardiol (Engl Ed). 2019 Mar; doi:10.1016/j.rec.2018.12.009. Epub 2019 Mar 28. PMID:30930255.

Thesis

Ramos R [Director]. Alex Vila Belmonte [PhD Student]. Estimación de la prevalencia de la Hipercolesterolemia Familiar y de las características clínicas asociadas en Cataluña. Universitat de Girona. 13/12/2019.

Ramos R, Elosua R [Director]. Gabriel Vázquez Oliva [PhD Student]. El síndrome coronario agudo: tendencias en la magnitud del problema, en el manejo hospitalario y en la aparición de complicaciones en un estudio de base poblacional. Universitat de Girona. 08/02/2019.

Ramos R, Garcia MD [Director]. Dídac Parramon Font [PhD Student]. Avaluació de la funció renal en la millora de la predicció del risc vascular. Anàlisi del rol de les estatines en la prevenció primària d?esdeveniments cardiovascular en la població amb malaltia renal crònica inicial. Universitat de Girona. 26/07/2019.

Ramos R, Garcia MD [Director]. Lourdes Camós Llovet [PhD Student]. Factors associated with arterial stiffness in a general Mediterranean population and in a Mediterranean intermediate cardiovascular risk population. Girona. Departament d'Infermeria, Universitat de Girona. 26/02/2019.

Indicators

Indicator

2019

Researchers with PhD

9

Total number of projects in which group members have participated

13

Total number of projects in which the PI of the project has belonged to the group

9

Total Funding

352.824,59€

Scientific publications in indexed journals

18

Total Impact factor

118,1

Nº of articles in Q1 journals

14

Q1 IF

108,946

Nº of articles in Q2 journals

2

Q2 IF

5,346

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