1. Annual report 2023
  2. Research
  3. GRECAP

GRECAP

Cardiovascular research group in primary care

The group is made up of seven family doctors, a preventive doctor and a graduate in Statistics, all working in Barcelona. 44% of its members are women. There are four doctors, two of whom are women and one more is finishing her doctoral thesis. The group has a recognized track record and was accredited as consolidated by AGAUR in 2021 (2021 SGR 01417). Within the group, several doctoral theses have been defended and another three are currently in progress.

The group's lines of work are specifically:

1. Heart Failure in Primary Care: Knowledge, attitudes and skills of patients and professionals regarding the management of heart failure. Evaluation of interventions.

2. High blood pressure and cardiovascular risk

3. Primary and secondary cardiovascular prevention

Group projects

R+D+I PROJECTS FUNDED IN COMPETITIVE CALLS FROM ADMINISTRATIONS OR PUBLIC AND PRIVATE ENTITIES

  • Premi trajectòria Investigadora AP Miguel A. Muñoz. ICS - Institut Català de la Salut. 2020 IP: Miguel Angel Muñoz Pérez.

  • A European Health Data Toolbox for Enhancing Cardiology Data Interoperability, Reusability and Privacy - DT4H. IP: Miguel Angel Muñoz Pérez

  • A non-inferiority randomized trial testing an advice of moderate drinking pattern versus advice on abstention on major disease and mortality. IP: Miguel Angel Muñoz Pérez (Miguel Angel Martínez González. Universidad de Navarra). European research Grant.

  • Investigación en insuficiencia cardíaca en atención primaria. ICS - Institut Català de la Salut. 2021-2023. IP: José María Verdú Rotellar.

  • Valor pronòstic del monitoratge ambulatori de pressió arterial de 24 hores sobre la incidència d´esdeveniments cardiovasculars en pacients en prevenció primària cardiovascular. (PREDOC_ECO-19/5). ICS - Institut Català de la Salut. 2020-2024. IP: Clara Puig Pera.

  • Hipertensió Ortostàtica, Pressió Ambulatòria i Fenotips Hipertensius.IP: Ernest Vinyoles Bargalló

CONTRACTS, AGREEMENTS OR NON-COMPETITIVE R+D+I PROJECTS WITH ADMINISTRATIONS OR PUBLIC OR PRIVATE ENTITIES.

  • Algoritme que et calcula el risc d'event cardiovascular en els propers 5 anys. IP: Ernest Vinyoles Bargalló

CLINICAL STUDIES

  • Validació externa de l'algoritme de risc del projecte "Valor pronòstic del monitoratge ambulatori de pressió arterial de 24 hores sobre la morbiditat i mortalitat cardiovascular en pacients en prevenció primària cardiovascular". ICS - Institut Català de la Salut. 2022-2025. IP: Ernest Vinyoles Bargalló.

  • Relación entre el SCORE H2PEF y la morbimortalidad de lospacientes con insuficiencia cardíaca con fracción de eyección. ICS - Institut Català de la Salut. 2022IP:José María Verdú Rotellar.

  • Proyecto PEEADE-SIDIAP: Seguimiento cardiovascular a largo plazo mediante SIDIAP de una cohorte sin enfermedad cardiovascular representativa de la población mayor de 64 años. Consorcio Centro de Investigación Biomédica en RED (CIBER). 2022. IP: José María Verdú Rotellar.

  • An International Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Outpatients in Early Stages of COVID-19. (INSIGHT 12). University of Minnesota. 2021 IP: Ernest Vinyoles Bargalló.

  • A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-5245 for the Treatmentof COVID-19 in Participants With High-Risk for Disease Progression. (GS-US-611-6273). Gilead Sciences, S.L. 2023 IP: Ernest Vinyoles Bargalló.

  • A multi-center, randomized, double-blind, parallel-group, 20-week dose-finding study to evaluate efficacy, safety, and tolerability of XXB750 in patients with resistant hypertension. (CXXB750B12201). Novartis Farmacéutica, S.A. 2023 IP: Ernest Vinyoles Bargalló.

Group Publications

JOURNAL PUBLICATIONS

  • Ras-Jiménez MDM, Ramos-Polo R, Francesch Manzano J, Corbella Santano M, Morillas Climent H, Jose-Bazán N, Jiménez-Marrero S, Garcimartin Cerezo P, Yun Viladomat S, Moliner Borja P, Torres Cardús B, Verdú-Rotellar JM, Diez-López C, González-Costello J, García-Romero E, de Frutos Seminario F, Triguero-Llonch L, Enjuanes Grau C, Tajes Orduña M, Comin-Colet J. Soluble Transferrin Receptor as Iron Deficiency Biomarker: Impact on Exercise Capacity in Heart Failure Patients. J Pers Med. 2023 Aug 21;13(8):1282. doi: 10.3390/jpm13081282. PMID: 37623532; PMCID: PMC10455097.

  • Martinez Urbistondo D, San Cristobal R, Villares P, Martinez Gonzalez MA, Babio N, Corella D et al. Role of NAFLD on the health related QoL response to lifestyle in patients with metabolic syndrome: The PREDIMED plus cohort (vol 13, 868795, 2022). Front. Endocrinol. 2023;13 PMID:36714565.

  • de la Sierra A, Ruilope LM, Martínez Camblor P, Vinyoles E, Gorostidi M, Segura J et al. Impact of timing of antihypertensive treatment on mortality: an observational study from the Spanish Ambulatory Blood Pressure Monitoring Registry. J. Hypertens. 2024;42(2):260-266. PMID:37796235.

  • Vinyoles E, Soldevila N. Hipotensión ortostática. FMC Formacion Med. Continuada Aten. Prim. 2023;30(1):30-32.

  • Troncoso Mariño A, Lestón Vázquez M, Gallardo Borge S, Del Val Garcia JL, Amado Guirado E, Violán C. Fracture risk after deprescription of bisphosphonates: Application of real-world data in primary care. Aten. Prim. 2023;55(7):102651-102651. PMID:37187104.

  • Rodriguez Calvo R, Granado Casas M, de Oca A, Julian MT, Domingo M, Codina P et al. Fatty Acid Binding Proteins 3 and 4 Predict Both All-Cause and Cardiovascular Mortality in Subjects with Chronic Heart Failure and Type 2 Diabetes Mellitus. Antioxidants. 2023;12(3): PMID:36978893.

  • Soldevila N, Vinyoles E, Tobias A, Muñoz Pérez MA, Gorostidi M, de la Sierra A. Effect of air pollutants on ambulatory blood pressure. Hipertens. Riesgo Vasc. 2023;40(3):119-125. PMID:37748946.

  • Muñoz Bravo C, Olmedo P, Gil F, Ruiz Canela M, Martínez González MA, Martínez MA et al. Association between serum copper levels and risk of cardiovascular disease: A nested case-control study in the PREDIMED trial. Nutr. Metab. Cardiovasc. Dis. 2023;33(11):2199-2208. PMID:37580236.

PROCEEDING PAPERS

  • De la Sierra A, Ruilope L, Gorostidi M, Vinyoles E, Segura J, Armario P et al. Prognosis of resistant hypertension, white-coat resistant hypertension, and refractory hypertension. J. Hypertens. 2023;4172-72.

  • Riverola AP, Yun S, Jose N, Hidalgo E, Ruiz M, Alcoberro L et al. Effect of telemedicine on self-care in heart failure patients: insights from the iCOR randomised controlled trial. Eur. Heart J. 2023;44

TECHNICAL DOCUMENTS

  • Mundet Tuduri X, Cegri F, Salvador B, Segura Anducas A, Cobo Guerrero S, Vinyoles Bargalló E et al. Consens català sobre atenció a la malaltia renal crònica (Consenso catalán sobre atención a la enfermedad renal crónica; Catalan consensus on chronic kidney disease care). 2023;

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