1. Annual report 2023
  2. Research
  3. ISAC

ISAC

Interventions in Health and Community Activities

Multidisciplinary cross-disciplinary group made up of 20 professionals (6 doctors and 5 doctoral students) of different profiles who carry out their research in Primary Care, frequently collaborating with other groups and entities. Her lines of research are related to interventions on lifestyles, preventive health promotion activities (nutrition, smoking, physical activity, vaccines), and quality and patient safety, with a focus on communities, using information and communication technologies (ICTs). Different members of the group have led projects funded in competitive calls (FIS, PERIS, IDIAPJGol, etc.) and have obtained funding from contracts and agreements with European entities. The group takes into account the gender perspective, citizen participation, dissemination and socialization of science. As for scientific dissemination, priority will be given to the publication "OpenAcces" and in the SCIENTIA digital repository of the Department of Health.

Group projects

R+D+I PROJECTS FUNDED IN COMPETITIVE CALLS FROM ADMINISTRATIONS OR PUBLIC AND PRIVATE ENTITIES

  • Utilidad y rendimiento de la detección de alteraciones espirométricas, mediante una aplicación móvil, en fumadores asintomáticos. ICS - Institut Català de la Salut. 2022-2026. IP: Darinka Savic Pesic.

  • Premi trajectòria investigadora infermera ICS 2022. ICS - Institut Català de la Salut. IP: Cristina Rey Reñones.

  • Plataforma IMPACT - Programa 1 Medicina Predictiva IMP/00021. (IMP/00021). Consoricio Centro de Investigación Biomédica en RED (CIBER); Instituto de Salud Carlos III. 2020. IP: Josep Basora Gallisà,Bonaventura Bolíbar Ribas.

  • Pla Estratègic de Recerca en Nutrició i Tabaquisme - Grup CENIT. (INTENS-19/7). ICS - Institut Català de la Salut. 2020-2023. IP: Francisco Martín Luján.

  • Intensificació ISCIII Cristina Rey. (INT23/00021). Instituto de Salud Carlos III. 2023IP:Cristina Rey Reñones.

  • Effectiveness of a motivational intervention based on spirometry results to achieve smoking cessation in primary healthcare patients: randomised, parallel, controlled multicentre study. COL·LEGI OFICIAL DE METGES DE TARRAGONA. IP: Francisco Martín Luján.

  • Efecte de la Dieta Mediterrània sobre la funció pulmonar en fumadors sense patologia respiratòria prèvia: l'assaig clínic MEDIS-TAR (Mediterranean Diet and Smoking in Tarragona). COL·LEGI OFICIAL DE METGES DE TARRAGONA. 2023-2026. IP: Francisco Martín Luján.

  • Efecte de la dieta mediterrània sobre la funció pulmonar en fumadors sense patologia respiratòria prèvia. 2018-2023. IP: Roxana-Elena Catalin -.

  • Alianza en Innovación e Industrialización Sanitaria del eje Mediterráneo. (PT20/00147). Instituto de Salud Carlos III. 2020-2024. IP: Josep Basora Gallisà.

CONTRACTS, AGREEMENTS OR NON-COMPETITIVE R+D+I PROJECTS WITH ADMINISTRATIONS OR PUBLIC OR PRIVATE ENTITIES.

  • Integració del farmacèutic/farmacòleg d'atenció primària en l'equip d'atenció primària. IP: Ferran Bejarano Romero.

  • IISPV: Estudi Qualitatiu sobre l'experiencia d'ús d'un dispositiu mòbil com a suport de diagnòstic i seguiment de retinopaties. 2022-2023. IP: Josep Basora Gallisà.

  • Dispositiu per netejar les mans de forma correcte (HigienICS). IP: Francisco Martín Luján.

  • App per a la teràpia dedeshabituació tabaquica. TOBBSTOP. IP: Cristina Rey Reñones.

CLINICAL STUDIES

  • VITTLINK: A multi-centre international database study evaluating the association of vaccine-induced thrombosis and thrombocytopenia (VITT) with COVID-19 vaccination. 2022-2024. IP:  Villalobos Martínez.

  • VAC4EU Postauthorisation Effectiveness Study of BIMERVAX® Vaccine in Europe. Research Triangle Institute (RTI). 2023-2026. IP: Felipe Villalobos Martínez.

  • Ús de dulaglutide als països europeus - Drug Utilization Study (DUS). Estudi transversal, multi-països amb múltiples fonts de dades sobre la utilització de medicaments utilitzant bases de dades electròniques. [Utilisation of dulaglutide in European countries: A cross-sectional, multi-country and multi-source drug utilisation study using electronic health record databases. IQVIA Information, S. A. 2017-2024. IP: Josep Basora Gallisà.

  • Self-controlled case series (SCCS) study of COVID-19 vaccines and myocarditis and pericarditis (GVDN-VAC4EU-Myocarditis). 2022-2024. IP: Felipe Villalobos Martínez.

  • Salud pública y Medicina preventiva de precisión combinando exploración física, hábitos de vida e información genómica: monitorización de la pandemia de obesidad a través de extensión de la Cohorte IMPaCT (Obes-IMPaCT). (PMP/00003). Instituto de Salud Carlos III. 2022 IP: Josep Basora Gallisà.

  • Risk of Guillain-Barré syndrome (GBS) after COVID-19 vaccination and SARS-CoV-2 infection: A self-controlled risk interval study. 2022-2024. IP: Felipe Villalobos Martínez.

  • Recolecció d'un fitxer de dades pel projecte MIT Open Voice COVID-19. Fundacio de Recerca Clinic Barcelona- Institut d'Investigacions Biomediques August Pi i Sunyer. 2020-2023. IP: Josep Basora Gallisà.

  • Rapid Safety Assessment of SARS-CoV-2 vaccines in EU Member States using electronic health care datasources (WP3). Vaccine Monitoring Collaboration for Europe (VAC4EU). 2021-2025. IP: Felipe Villalobos Martínez.

  • Projecte validació de mascaretes FFP2-CSIC. Gomà-Camps, S.A.U. 2021-2024. IP: Josep Basora Gallisà.

  • Post-Conditional Approval Active Surveillance Study Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID -19) Vaccine. Fondazione Penta ONLUS. 2021-2024. IP: Felipe Villalobos Martínez.

  • Post-Authorization Active Surveillance Safety Study Using Secondary Data to Monitor Real-World Safety of Spikevax in Europe. ICS - Institut Català de la Salut; Julius Clinical Research B.V. 2021-2024. IP: Felipe Villalobos Martínez.

  • Monitoring safety of Spikevax in pregnancy: an observational study using routinely collected health data in five European countries. Julius Clinical Research B.V. 2021-2024. IP: Felipe Villalobos Martínez.

  • Impacte d'un test diagnòstic ràpid que permet discriminar l'origen viral del bacterià en les infeccions respiratòries agudes (IRA) del tracte superior en edat pediàtrica. 2021IP:Josep Basora Gallisà.

  • Evaluación del nivel de biomarcadores de efecto y exposición a la contaminación del aire en muestras de sangre y orina de residentes dependiendo de la distancia al complejo petroquímico (PETROMARKER). 2021-2024. IP: Francisco Martín Luján.

  • Evaluación de SINERGIAPS, una intervención dirigida a mejorar la seguridad del paciente en centros de salud en España en base a las percepciones y experiencias de los propios pacientes. 2023-2023. IP: Montserrat Gens Barberà.

  • Evaluación de la seguridad del paciente en atención primaria en España en base a las percepciones y experiencias de los propios pacientes: Estudio SINERGIAPS 2. (PI22/01822). Instituto de Salud Carlos III. 2022 IP: Montserrat Gens Barberà.

  • Eficàcia d'una formació online en maniobres de Ressuscitació cardiopulmonar i l'ús del Desfibril·lador Extern Automatitzat (DEA) a través d'una plataforma virtual. 2023-2026. IP:  Rey Reñones.

  • Effectiveness of heterologous and booster Covid-19 vaccination in 5 European countries, using a cohort approach in children and adults with a full primary Covid-19 vaccination regimen. UMC Utrecht (University Medical Center Utrecht). 2022-2024. IP: Felipe Villalobos Martínez.

  • EFECTIVITAT D'UNA INTERVENCIÓ EDUCATIVA SOBRE LA HIGIENE DE MANS EN ALUMNAT D'ESCOLES SENTINELLA. 2023-2026. IP: Josep Basora Gallisà.

  • Efectividad de una aplicación para dispositivos móviles en la deshabituación de tabaco en mujeres embarazadas (TOBBGEST): ensayo comunitario aleatorio. (PI21/01058). Instituto de Salud Carlos III. 2021. IP: Cristina Rey Reñones.

  • Disseny i avaluació d'una plataforma interactiva d'activitats comunitàries promogudes des de l'atenció primària per a fomentar la salut i el benestar en una població d'una àrea bàsica de salut. (SLT021/21/000073). Generalitat Catalunya.Departament de Salut. 2022IP:Maria Roser Pedret Llaberia.

  • Cohort Event Monitoring of safety of COVID-19 vaccines in special populations (pregnant and lactating women, children and adolescents, immunocompromised, people with history of allergy, people with prior SARS-CoV-2 infection) (WP1). European Medicines Agency (EMA). 2021-2024. IP: Felipe Villalobos Martínez.

  • Clinical course, outcomes and risk factors of myocarditis following administration of mRNA-1273 (ELASOMERAN). Julius Clinical Research B.V. 2023-2025. IP: Felipe Villalobos Martínez.

  • An Observational Post-Authorization Safety Study to Assess the Safety of Ad26.COV2.S Using European Healthcare Data through VAC4EU. TEAMIT INSTITUTE, S.L. 2021-2024. IP: Felipe Villalobos Martínez.

  • Post-Authorisation Active Surveillance Study of Myocarditis and Pericarditis Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID 19) Vaccine. Fondazione Penta ONLUS. 2022-2025. IP: Felipe Villalobos Martínez.

  • Estudio posautorización de seguridad (EPAS) no intervencionista para la vigilancia activa de la seguridad de los receptores de la vacuna de ARNm contra la COVID-19 de Pfizer-BioNTech en la UE. Pfizer, S.A. 2021 IP: Felipe Villalobos Martínez.

Group publications

JOURNAL PUBLICATIONS

  • Santigosa Ayala A, Magrané Francesch E, Mora Sansaloni A. Water-induced lesions on the palms: Presentation of a case of aquagenic keratoderma. Aten. Prim. 2023;55(12):102753-102753. PMID:37690339.

  • Kou XR, Iglesias Vázquez L, Nadal M, Basora J, Arija V. Urinary concentrations of heavy metals in pregnant women living near a petrochemical area according to the industrial activity. Environ. Res. 2023;235116677-116677. PMID:37454794.

  • Aragones E, Rodoreda S, Guitart M, Garcia E, Berenguera A, Martin F et al. Study protocol: assessment of the usefulness and practicability of a psychoeducational intervention to prevent the negative psychological impact of the COVID-19 pandemic on primary care health workers. BMC Prim. Care. 2023;24(1):231-231. PMID:37925394.

  • Rambla C, Aragonès E, Pallejà Millán M, Tomé Pires C, López Cortacans G, Sánchez Rodríguez E et al. Short and long-term predictors of pain severity and interference in primary care patients with chronic musculoskeletal pain and depression. BMC Musculoskelet. Disord. 2023;24(1):270-270. PMID:37020278.

  • Ahmadizar F, Luxi N, Raethke M, Schmikli S, Riefolo F, Saraswati PW et al. Safety of COVID-19 Vaccines Among the Paediatric Population: Analysis of the European Surveillance Systems and Pivotal Clinical Trials. Drug Saf. 2023;46(6):575-585. PMID:37103643.

  • Martinez Urbistondo D, San Cristobal R, Villares P, Martinez Gonzalez MA, Babio N, Corella D et al. Role of NAFLD on the health related QoL response to lifestyle in patients with metabolic syndrome: The PREDIMED plus cohort (vol 13, 868795, 2022). Front. Endocrinol. 2023;13PMID:36714565.

  • Solanes Cabus M, Paredes E, Limon E, Basora J, Alarcon I, Veganzones I et al. Primary and Community Care Transformation in Post-COVID Era: Nationwide General Practitioner Survey. Int J Environ Res Public Health. 2023;20(2):PMID:36674354.

  • Motevalizadeh E, Diaz Lopez A, Martin Lujan F, Basora J, Arija V. Prenatal Factors Associated with Maternal Cardiometabolic Risk Markers during Pregnancy: The ECLIPSES Study. Nutrients. 2023;15(5):PMID:36904135.

  • Catalin RE, Martin Lujan F, Salamanca Gonzalez P, Palleja Millan M, Villalobos F, Santigosa Ayala A et al. Mediterranean Diet and Lung Function in Adults Current Smokers: A Cross-Sectional Analysis in the MEDISTAR Project. Nutrients. 2023;15(5):PMID:36904270.

  • Iglesias Vazquez L, Gimeno M, Coronel P, Caspersen IH, Basora J, Arija V. Maternal factors associated with iron deficiency without anaemia in early pregnancy: ECLIPSES study. Ann. Hematol. 2023;102(4):741-748. PMID:36790457.

  • Martinez Torres S, Mesquida Veny F, Del Rio JA, Hervera A. Injury-induced activation of the endocannabinoid system promotes axon regeneration. iScience. 2023;26(6):PMID:37235048.

  • Pepió Espuny M, Ortega Vila Y, Aragonès Benaiges E, Fernández Sáez J, Pallejà Millán M, Cabré Vila JJ. Influencia del género y el lugar de residencia sobre la evolución y mortalidad de la cardiopatía isquémica en Cataluña: un estudio de base poblacional. Rev Esp Salud Publica. 2023;97PMID:36655384.

  • Iglesias Vázquez L, Voltas N, Hernández Martínez C, Canals J, Coronel P, Gimeno M et al. Importance of Maternal Iron Status on the Improvement of Cognitive Function in Children After Prenatal Iron Supplementation. Am. J. Prev. Med. 2023;65(3):395-405. PMID:36906495.

  • Martín Luján F, Santigosa Ayala A, Pallejà Millán M, Rey Reñones C, Villalobos F, Solà R et al. Effectiveness of the spirometry-based motivational intervention to quit smoking: RESET randomised trial. Eur. J. Gen. Pract. 2023;29(1):2276764-2276764. PMID:37933978.

  • Riefolo F, Castillo Cano B, Martín Pérez M, Messina D, Elbers R, Brink Kwakkel D et al. Effectiveness of homologous/heterologous booster COVID-19 vaccination schedules against severe illness in general population and clinical subgroups in three European countries. Vaccine. 2023;41(47):7007-7018. PMID:37858451.

  • Romero Aroca P, Verges R, Pascual Fontanilles J, Valls A, Franch J, Barrot J et al. Effect of Lipids on Diabetic Retinopathy in a Large Cohort of Diabetic Patients after 10 Years of Follow-Up. J Clin Med. 2023;12(20):PMID:37892811.

  • Gentille Lorente D, Hernández Pinilla A, Satue Gracia E, Muria Subirats E, Forcadell Peris MJ, Gentille Lorente J et al. Echocardiography and Electrocardiography in Detecting Atrial Cardiomyopathy: A Promising Path to Predicting Cardioembolic Strokes and Atrial Fibrillation. J Clin Med. 2023;12(23):PMID:38068367.

  • Pujolar Díaz G, Vidal Alaball J, Forcada A, Descals Singla E, Basora J, PECT BAGESS GRP. Creation of a Laboratory for Statistics and Analysis of Dependence and Chronic Conditions: Protocol for the Bages Territorial Specialization and Competitiveness Project (PECT BAGESS). JMIR RES. Protoc. 2023;12PMID:37494102.

  • Motevalizadeh E, Díaz López A, Martín F, Basora J, Arija V. Association of Parity With Insulin Resistance Early in Pregnant Women: ECLIPSES Study. J. Clin. Endocrinol. Metab. 2023;109(3):730-739. PMID:37804535.

PROCEEDING PAPERS

  • Aarts W, Choi J, Roy D, Fry C, Lane S, Gini R et al. VAC4EU study tracking post-authorization safety of mRNA-1273 in five European countries: How to overcome the methodological challenges. Pharmacoepidemiol. Drug Saf. 2023;3267-67.

  • Zwiers L, Goodale B, Aarts W, Esposito D, St Laurent S, Martin D et al. VAC4EU study to identify risk factors for the development of myocarditis and pericarditis after mRNA1273 vaccination in four European countries: Methodological considerations. Trop. Med. Int. Health. 2023;2882-83.

  • Bots SH, Belitser SV, Durán CE, Riera Arnau J, Schultze A, Messina D et al. Using negative control outcomes to identify unmeasured confounding in a self-controlled risk interval study evaluating the COVID-19 vaccine myocarditis safety signal. Pharmacoepidemiol. Drug Saf. 2023;3255-56.

  • Raethke M, Luxi N, Trifirò G, Thurin NH, Mentzer D, De Clercq E et al. Safety monitoring of COVID-19 vaccines in multiple European countries: Initial results from the COVID-19 vaccine monitor (CVM). Pharmacoepidemiol. Drug Saf. 2023;32151-152.

  • Durán CE, Belitser SV, Bots SH, Riefolo F, Messina D, Gini R et al. Myocarditis associated with SARS-CoV-2 vaccines by dose and brand in three European countries using large electronic health care data sources: A self-controlled risk interval study in the COVID-19 vaccine monitor study. Pharmacoepidemiol. Drug Saf. 2023;3241-42.

  • Durán CE, Riefolo F, Gini R, Messina D, García Poza P, Martín Perez M et al. Incidence of COVID-19 disease severity in a cohort of 4.4 million Italian and Spanish children from six healthcare databases. Pharmacoepidemiol. Drug Saf. 2023;32138-139.

  • Iglesias Vázquez L, Aranda N, Aparicio E, Basora J, Arija V. Adjusting prenatal iron supplementation to women's needs in early pregnancy to improve maternal iron status in late pregnancy. Ann. Nutr. Metab. 2023;79583-583.

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