1. Annual report 2024
  2. Research
  3. GRIP

GRIP

Research Group on Infections in Primary Care

The group is made up of family doctors who work in different lines of research on infectious diseases in primary care. We have collaborations with Catalan, Spanish and international universities and Catalan and foreign primary care scientific societies. We actively participate in research by independent organizations in Catalonia, Spain and abroad.

The primary objective of the group is to encourage a more reasoned prescription of antimicrobials in primary care, identifying the subgroups of patients who really need them and avoiding them when they are not needed. Other objectives are the microbiological aspects of the most prevalent community germs, identifying whether the etiology is bacterial or viral, resistance and prognosis of the most common infections. Another objective is to provide the family doctor with diagnostic tools in community infections through rapid diagnostic methods.

Group projects

  • Optimization in the use of antibiotics for community infections in primary care GRIP. (SENIOR-23/2). ICS - Catalan Institute of Health. 2024-2028. PI: Carles Llor Vilà.
  • Improvement in the use of antibiotics for urinary tract infections in primary care. ICS - Catalan Institute of Health. 2022-2024. IP: Ana Moragas Moreno.
  • Predictors of acute pyelonephritis in people suffering from a urinary tract infection (WP3) - ITUCAT study. 2024-2027. IP: Ana Moragas Moreno.
  • POS-ARI-PC-001: Study on the incidence of medically-attended respiratory syncytialvirus, human metapneumovirus and human parainfluenza virus amongst older adults in Europe. ECRAID-Core. 2024-2027. IP: Carles Llor Vilà. Spanish primary care clinicians' attitudes towards point-of-care blood testing for respiratory tract infections in adults in primary care. A qualitative study. 2024-2026. IP: Ana Moragas Moreno.
  • Pandemic Information to Support Rapid Response - PAIR. (101133191). European Commission. 2024-2028. IP: Carles Llor Vilà.
  • Grau d'adequació en la Sol·licitud d'Urocultius procedents d'Atenció Primària (WP4). ITUCAT. 2023-2026. IP: Ana Moragas Moreno. Perpetual Observational Study (POS) of Acute Respiratory Infections (ARI) in primary care settings (PC) across Europe - Audit. UMC Utrecht (University Medical Center Utrecht). 2023-2026. IP: Carles Llor Vilà. Tailoring antibiotic therapy duration for uncomplicated respiratory tract infections that need antibiotic therapy.
  • The pre-STORM qualitative study (Adaptació de la durada del tractament antibiòtic de les infeccions respiratòries no complicades que necessiten antibioteràpia. L'estudi qualitatiu pre-STORM). 2023-2026. IP: Ana Moragas Moreno. European Clinical Research Alliance on Infectious Diseases
  • Primary care adaptive platform trial for pandemics and epidemics (ECRAID-Prime). UMC Utrecht (University Medical Center Utrecht). 2023-2026. IP: Carles Llor Vilà. Improving antibiotic use in long term care facilities by infection prevention and control and antibiotic stewardship (IMAGINE). European Commission. 2022-2025. IP: Carles Llor Vilà.
  • Imroving Antibiotic prescribinG In NursIng homEs in Spain. A before and after intervention study (IMAGINE-SPAIN Study). (ID 71388143). Pfizer, S.L.U. 2022-2025. IP: Carles Llor Vilà. First void OR Midstream Urine sampling among women with Lower urinAry tract infection symptoms. ICS - Institut Català de la Salut. 2022-2025. IP: Ana Moragas Moreno.
  • Maneig de les ITUS a Catalunya: estudi descriptiu del maneig diagnòstic i terapèutic, i l'impacte de les teràpies supressores en la gravetat d'infeccions potencialment greus [Estudi ITUCAT]. (SLT021/21/000022). Generalitat Catalunya. 2022-2025. IP: Ana Moragas Moreno.
  • Platform randomised controlled trial of point of care diagnostics for enhancing the quality of antibiotic prescribing for community acquired acute respiratory tract infection in ambulatory care in Europe (PRUDENCE). University of Oxford. 2020-2025. IP: Carles Llor Vilà.
  • Efectividad clínica y erradicación bacteriológica de 4 pautas antibióticas cortas en infecciones urinarias en mujeres adultas. estudio SCOUT. (ICI20/00100). Instituto de Salud Carlos III. 2020-2026. IP: Carles Llor Vilà.
  • Health Alliance for Prudent Prescription and Yield of Antibiotics in a Patient-centred Perspective (HAPPY PATIENT). European Commission. 2020-2024. IP: Carles Llor Vilà.

Group Publications

  • Llor C, Moragas A, Ruppe G, Lykkegaard J, Hansen MP, Antsupova VS et al. Diagnosing probable urinary tract infections in nursing home residents without indwelling catheters: a narrative review. Clin. Microbiol. Infect. 2024; 30(12):1523-1528. PMID:39209268.
  • Llor C, Rodríguez Bernuz C, Troncoso Mariño A. Antibiotic use in Barcelona in 2023 in primary care and the potential reduction by adjusting box sizes to current guidelines. Rev. Esp. Quim. 2024; 37(6):PMID:39348221.
  • García Sangenis A, Lykkegaard J, Hansen MP, López Valcárcel B, Raynal F, Vallejo Torres L et al. Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. The HAPPY PATIENT project. Fam. Pr. 2024; 42(2):PMID:39531344.
  • Moragas A, Sarvisé C, Gómez F, Picó Plana E, Crispi S, Llor C. Duration of severe and moderate symptoms in pharyngitis by cause. Aten Primaria. 2024; 56(11):102994-102994. PMID:38875835.
  • Llor C. Health administration key role in curbing antimicrobial resistance. Med Clin (Barc). 2024;163(7):372-373. PMID:38926036.
  • Llinas A, Paredes E, Sol J, Palacin JM, Solanes M, Martinez J et al. Impact of Lung Ultrasound along with C-Reactive Protein Point-of-Care Testing on Clinical Decision-Making and Perceived Usefulness in Routine Healthcare for Patients with Lower Respiratory Tract Infections: Protocol for Analytical Observational Study. J Clin Med. 2024;13(19):PMID:39407829.
  • Llor C, Frimodt Moller N, Miravitlles M, Kahlmeter G, Bjerrum L. Optimising antibiotic exposure by customising the duration of treatment for respiratory tract infections based on patient needs in primary care. EClinicalMedicine. 2024;74102723-102723. PMID:39070175.
  • Llor C. Comment on: Community-acquired pneumonia: a US perspective on the guideline gap. J Antimicrob Chemother. 2024;79(8):2079-2079. PMID:38959332.
  • Llor C, Benko R, Bjerrum L. Global restriction of the over-the-counter sale of antimicrobials: does it make sense?. Front. Public Health. 2024;121412644-1412644. PMID:39022420.
  • Llor C, Trapero Bertran M, Sisó Almirall A, Monfà R, Abellana R, García Sangenís A et al. Effects of C-reactive protein rapid testing and communication skills training on antibiotic prescribing for acute cough. A cluster factorial randomised controlled trial. npj Prim. Care Respir. Med. 2024;34(1):9-9. PMID:38724543.
  • Llor C, Moragas A. A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials. Expert Rev Anti Infect Ther. 2024;22(5):277-278. PMID:38381126.
  • Matovelle P, Olivan Blázquez B, Magallón Botaya R, García Sangenís A, Monfà R, Morros R et al. Antimicrobial Agent Use for Urinary Tract Infection in Long-Term Care Facilities in Spain: Results from a Retrospective Analytical Cohort Analysis. Antibiotics (Basel). 2024;13(2):PMID:38391537.
  • Moragas A, Uguet P, Cots JM, Boada A, Bjerrum L, Llor C. Perception and views about individualising antibiotic duration for respiratory tract infections when patients feel better: a qualitative study with primary care professionals. BMJ Open. 2024;14(2):PMID:38316598.
  • Garcia Sangenis A, Modena D, Jensen JN, Chalkidou A, Antsupova VS, Marloth T et al. Improving Antibiotic Use in Nursing Homes by Infection Preventionand Control and Antibiotic Stewardship (IMAGINE):Protocol fora Before-and-After Intervention and Implementation Study. JMIR Res Protoc. 2024;13PMID:39284176.
  • García Sangenís A, Fernández García S, Chalkidou A, Nygaard Jensen J, Marloth T, Antsupova VS et al. Urinary Tract Infection Diagnosis and Management in Eight European Countries: Results of a Context Analysis Study. Pharmacoepidemiol Drug Saf. 2024;33281-282.
  • Lambert M, Benko R, Lykkegaard J, Hansen MP, Floriano FR, Llor C et al. The HAPPY PATIENT Project: Measuring and Improving Community Antibiotic Dispensing in Europe. Pharmacoepidemiol Drug Saf. 2024;33280-280.
  • Escolà RM, Sangenís AG, Pedrós RM, Nozal JM, Bejar CS, Jiménez CR et al. Improving antibiotic prescribing in nursing homes in Spain: A before-and-after intervention study. Basic Clin. Pharmacol. Toxicol. 2024;13550-51.
  • Sangenis AG, Escola RM, Pedros RM, Moreno AM, Vila CL. Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. Basic Clin. Pharmacol. Toxicol. 2024;13534-34.
  • Garcia SF, Moreno AM, Soriano MG, Llor C, Campos AR, Ouchi D et al. Urinary tract infections in women: Trends in antibiotic treatment over 10 years in Catalonia, Spain. Basic Clin. Pharmacol. Toxicol. 2024;13555-55.
Anar a l'inici